WormBase Tree Display for Gene: WBGene00004320
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| WBGene00004320 | Evidence | Accession_evidence | EMBL | AB077287 | |||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | ZK287 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | rbx-1 | |||||||
| Sequence_name | ZK287.5 | ||||||||
| Molecular_name | ZK287.5 | ||||||||
| ZK287.5.1 | |||||||||
| CE06614 | |||||||||
| Other_name | Ce-rbx-1 | Accession_evidence | EMBL | AB077287 | |||||
| CELE_ZK287.5 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | rbx-1 | ||||||||
| DB_info | Database | AceView | gene | 5K170 | |||||
| WormQTL | gene | WBGene00004320 | |||||||
| WormFlux | gene | WBGene00004320 | |||||||
| NDB | locus_tag | CELE_ZK287.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004320|UniProtKB=Q23457 | |||||||
| family | PTHR11210 | ||||||||
| NCBI | gene | 179358 | |||||||
| RefSeq | protein | NM_073095.8 | |||||||
| SwissProt | UniProtAcc | Q23457 | |||||||
| TREEFAM | TREEFAM_ID | TF105503 | |||||||
| UniProt_GCRP | UniProtAcc | Q23457 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rbx | ||||||||
| Allele (14) | |||||||||
| Strain | WBStrain00035875 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00000145 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00019993 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | The rbx-1 gene encodes an ortholog of the mammalian RING box protein RBX1 (or ROC1), which interacts with several cullins and is a subunit of both the von Hippel-Lindau (VHL) tumor suppressor complex and of the SCF ubiquitin-ligase (E3) complex. | Paper_evidence | WBPaper00012760 | |||||
| WBPaper00012766 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable cullin family protein binding activity and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of intracellular signal transduction; positive regulation of metaphase/anaphase transition of meiotic cell cycle; and sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation. Part of Cul2-RING ubiquitin ligase complex. Expressed in germ line; gonad; linker cell; and oocyte. Is an ortholog of human RBX1 (ring-box 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK287.5 | |||||||
| Corresponding_transcript | ZK287.5.1 | ||||||||
| Other_sequence (79) | |||||||||
| Associated_feature | WBsf655582 | ||||||||
| WBsf234258 | |||||||||
| WBsf234259 | |||||||||
| Experimental_info | RNAi_result (59) | ||||||||
| Expr_pattern | Expr2794 | ||||||||
| Expr2795 | |||||||||
| Expr2887 | |||||||||
| Expr12882 | |||||||||
| Expr1012451 | |||||||||
| Expr1032145 | |||||||||
| Expr1162760 | |||||||||
| Expr2015276 | |||||||||
| Expr2033510 | |||||||||
| Drives_construct | WBCnstr00023036 | ||||||||
| WBCnstr00035565 | |||||||||
| Construct_product | WBCnstr00035565 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (125) | |||||||||
| Interaction (133) | |||||||||
| Map_info | Map | V | Position | 2.06847 | Error | 0.00086 | |||
| Positive | Positive_clone | ZK287 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (24) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
