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WormBase Tree Display for Gene: WBGene00004320

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Name Class

WBGene00004320EvidenceAccession_evidenceEMBLAB077287
SMapS_parentSequenceZK287
IdentityVersion1
NameCGC_namerbx-1
Sequence_nameZK287.5
Molecular_nameZK287.5
ZK287.5.1
CE06614
Other_nameCe-rbx-1Accession_evidenceEMBLAB077287
CELE_ZK287.5Accession_evidenceNDBBX284605
Public_namerbx-1
DB_infoDatabaseAceViewgene5K170
WormQTLgeneWBGene00004320
WormFluxgeneWBGene00004320
NDBlocus_tagCELE_ZK287.5
PanthergeneCAEEL|WormBase=WBGene00004320|UniProtKB=Q23457
familyPTHR11210
NCBIgene179358
RefSeqproteinNM_073095.8
SwissProtUniProtAccQ23457
TREEFAMTREEFAM_IDTF105503
UniProt_GCRPUniProtAccQ23457
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrbx
Allele (14)
StrainWBStrain00035875
RNASeq_FPKM (74)
GO_annotation (23)
Ortholog (35)
ParalogWBGene00000145Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00019993Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionThe rbx-1 gene encodes an ortholog of the mammalian RING box protein RBX1 (or ROC1), which interacts with several cullins and is a subunit of both the von Hippel-Lindau (VHL) tumor suppressor complex and of the SCF ubiquitin-ligase (E3) complex.Paper_evidenceWBPaper00012760
WBPaper00012766
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable cullin family protein binding activity and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of intracellular signal transduction; positive regulation of metaphase/anaphase transition of meiotic cell cycle; and sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation. Part of Cul2-RING ubiquitin ligase complex. Expressed in germ line; gonad; linker cell; and oocyte. Is an ortholog of human RBX1 (ring-box 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK287.5
Corresponding_transcriptZK287.5.1
Other_sequence (79)
Associated_featureWBsf655582
WBsf234258
WBsf234259
Experimental_infoRNAi_resultWBRNAi00072808Inferred_automaticallyRNAi_primary
WBRNAi00117323Inferred_automaticallyRNAi_primary
WBRNAi00084286Inferred_automaticallyRNAi_primary
WBRNAi00085628Inferred_automaticallyRNAi_primary
WBRNAi00075176Inferred_automaticallyRNAi_primary
WBRNAi00072809Inferred_automaticallyRNAi_primary
WBRNAi00076881Inferred_automaticallyRNAi_primary
WBRNAi00075179Inferred_automaticallyRNAi_primary
WBRNAi00098117Inferred_automaticallyRNAi_primary
WBRNAi00117325Inferred_automaticallyRNAi_primary
WBRNAi00092091Inferred_automaticallyRNAi_primary
WBRNAi00098116Inferred_automaticallyRNAi_primary
WBRNAi00059331Inferred_automaticallyRNAi_primary
WBRNAi00092095Inferred_automaticallyRNAi_primary
WBRNAi00117328Inferred_automaticallyRNAi_primary
WBRNAi00092088Inferred_automaticallyRNAi_primary
WBRNAi00098137Inferred_automaticallyRNAi_primary
WBRNAi00116003Inferred_automaticallyRNAi_primary
WBRNAi00117327Inferred_automaticallyRNAi_primary
WBRNAi00108578Inferred_automaticallyRNAi_primary
WBRNAi00115988Inferred_automaticallyRNAi_primary
WBRNAi00075183Inferred_automaticallyRNAi_primary
WBRNAi00117322Inferred_automaticallyRNAi_primary
WBRNAi00038255Inferred_automaticallyRNAi_primary
WBRNAi00075180Inferred_automaticallyRNAi_primary
WBRNAi00084871Inferred_automaticallyRNAi_primary
WBRNAi00063397Inferred_automaticallyRNAi_primary
WBRNAi00117329Inferred_automaticallyRNAi_primary
WBRNAi00081626Inferred_automaticallyRNAi_primary
WBRNAi00009463Inferred_automaticallyRNAi_primary
WBRNAi00086633Inferred_automaticallyRNAi_primary
WBRNAi00117321Inferred_automaticallyRNAi_primary
WBRNAi00075181Inferred_automaticallyRNAi_primary
WBRNAi00092087Inferred_automaticallyRNAi_primary
WBRNAi00117330Inferred_automaticallyRNAi_primary
WBRNAi00092086Inferred_automaticallyRNAi_primary
WBRNAi00117326Inferred_automaticallyRNAi_primary
WBRNAi00094802Inferred_automaticallyRNAi_primary
WBRNAi00108653Inferred_automaticallyRNAi_primary
WBRNAi00086631Inferred_automaticallyRNAi_primary
WBRNAi00117320Inferred_automaticallyRNAi_primary
WBRNAi00027066Inferred_automaticallyRNAi_primary
WBRNAi00075178Inferred_automaticallyRNAi_primary
WBRNAi00086632Inferred_automaticallyRNAi_primary
WBRNAi00063616Inferred_automaticallyRNAi_primary
WBRNAi00072807Inferred_automaticallyRNAi_primary
WBRNAi00092093Inferred_automaticallyRNAi_primary
WBRNAi00098059Inferred_automaticallyRNAi_primary
WBRNAi00075177Inferred_automaticallyRNAi_primary
WBRNAi00092090Inferred_automaticallyRNAi_primary
WBRNAi00108346Inferred_automaticallyRNAi_primary
WBRNAi00084285Inferred_automaticallyRNAi_primary
WBRNAi00086630Inferred_automaticallyRNAi_primary
WBRNAi00117319Inferred_automaticallyRNAi_primary
WBRNAi00108347Inferred_automaticallyRNAi_primary
WBRNAi00103659Inferred_automaticallyRNAi_primary
WBRNAi00092085Inferred_automaticallyRNAi_primary
WBRNAi00117324Inferred_automaticallyRNAi_primary
WBRNAi00075182Inferred_automaticallyRNAi_primary
Expr_patternExpr2794
Expr2795
Expr2887
Expr12882
Expr1012451
Expr1032145
Expr1162760
Expr2015276
Expr2033510
Drives_constructWBCnstr00023036
WBCnstr00035565
Construct_productWBCnstr00035565
Microarray_results (25)
Expression_cluster (125)
Interaction (133)
Map_infoMapVPosition2.06847Error0.00086
PositivePositive_cloneZK287Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (24)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene