WormBase Tree Display for Gene: WBGene00004286
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| WBGene00004286 | SMap | S_parent | Sequence | D2013 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rab-39 | Person_evidence | WBPerson451 | |||||
| Sequence_name | D2013.1 | ||||||||
| Molecular_name | D2013.1 | ||||||||
| D2013.1.1 | |||||||||
| CE30340 | |||||||||
| Other_name | CELE_D2013.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | rab-39 | ||||||||
| DB_info | Database | AceView | gene | 2J612 | |||||
| WormQTL | gene | WBGene00004286 | |||||||
| WormFlux | gene | WBGene00004286 | |||||||
| NDB | locus_tag | CELE_D2013.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004286|UniProtKB=Q18969 | |||||||
| family | PTHR47979 | ||||||||
| NCBI | gene | 183941 | |||||||
| RefSeq | protein | NM_063583.4 | |||||||
| SwissProt | UniProtAcc | Q18969 | |||||||
| UniProt_GCRP | UniProtAcc | Q18969 | |||||||
| OMIM | gene | 300774 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rab | ||||||||
| Allele (29) | |||||||||
| Strain | WBStrain00055386 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (45) | |||||||||
| Paralog (32) | |||||||||
| Structured_description | Concise_description | rab-39 encodes a small, monomeric Rab GTPase that is most closely related to the human and Drosophila Rab39 GTPases; by homology, RAB-39 is predicted to function as a membrane-associated GTPase required for intracellular vesicular trafficking and for regulation of endo- and exocytosis; however, as loss of rab-39 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of RAB-39 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00004968 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00015788 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables GTP binding activity. Involved in positive regulation of response to oxidative stress. Predicted to be located in Golgi apparatus; cytoplasmic vesicle membrane; and plasma membrane. Expressed in head mesodermal cell; head neurons; hypodermis; rectal gland cell; and tail neurons. Human ortholog(s) of this gene implicated in Waisman syndrome and non-syndromic X-linked intellectual disability 72. Is an ortholog of human RAB39A (RAB39A, member RAS oncogene family) and RAB39B (RAB39B, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112059 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16499) | ||||
| DOID:0111781 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16499) | ||||||
| Molecular_info | Corresponding_CDS | D2013.1 | |||||||
| Corresponding_CDS_history | D2013.1:wp74 | ||||||||
| Corresponding_transcript | D2013.1.1 | ||||||||
| Other_sequence (25) | |||||||||
| Associated_feature | WBsf650420 | ||||||||
| WBsf650421 | |||||||||
| WBsf223635 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00101872 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00107759 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091937 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00012560 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030377 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112237 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107758 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00043437 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00101873 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11318 | ||||||||
| Expr1021236 | |||||||||
| Expr1032121 | |||||||||
| Expr1147433 | |||||||||
| Expr2015226 | |||||||||
| Expr2033460 | |||||||||
| Drives_construct | WBCnstr00018768 | ||||||||
| WBCnstr00035586 | |||||||||
| Construct_product | WBCnstr00035586 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (95) | |||||||||
| Interaction (23) | |||||||||
| Map_info | Map | II | Position | 1.15927 | Error | 0.011529 | |||
| Positive | Positive_clone | D2013 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00029101 | ||||||||
| WBPaper00030935 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041898 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00058949 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
