WormBase Tree Display for Gene: WBGene00004286
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WBGene00004286 | SMap | S_parent | Sequence | D2013 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | rab | ||||||
Allele (29) | |||||||
Strain | WBStrain00055386 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (18) | |||||||
Ortholog (45) | |||||||
Paralog (32) | |||||||
Structured_description | Concise_description | rab-39 encodes a small, monomeric Rab GTPase that is most closely related to the human and Drosophila Rab39 GTPases; by homology, RAB-39 is predicted to function as a membrane-associated GTPase required for intracellular vesicular trafficking and for regulation of endo- and exocytosis; however, as loss of rab-39 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of RAB-39 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00004968 | |||
WBPaper00005654 | |||||||
WBPaper00015788 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables GTP binding activity. Involved in positive regulation of response to oxidative stress. Predicted to be located in Golgi apparatus; cytoplasmic vesicle membrane; and plasma membrane. Expressed in head mesodermal cell; head neurons; hypodermis; rectal gland cell; and tail neurons. Human ortholog(s) of this gene implicated in Waisman syndrome and non-syndromic X-linked intellectual disability 72. Is an ortholog of human RAB39A (RAB39A, member RAS oncogene family) and RAB39B (RAB39B, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0112059 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16499) | ||
DOID:0111781 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16499) | ||||
Molecular_info | Corresponding_CDS | D2013.1 | |||||
Corresponding_CDS_history | D2013.1:wp74 | ||||||
Corresponding_transcript | D2013.1.1 | ||||||
Other_sequence (25) | |||||||
Associated_feature | WBsf650420 | ||||||
WBsf650421 | |||||||
WBsf223635 | |||||||
Experimental_info | RNAi_result | WBRNAi00101872 | Inferred_automatically | RNAi_primary | |||
WBRNAi00107759 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00091937 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00012560 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00030377 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00112237 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00107758 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00043437 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00101873 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr11318 | ||||||
Expr1021236 | |||||||
Expr1032121 | |||||||
Expr1147433 | |||||||
Expr2015226 | |||||||
Expr2033460 | |||||||
Drives_construct | WBCnstr00018768 | ||||||
WBCnstr00035586 | |||||||
Construct_product | WBCnstr00035586 | ||||||
Microarray_results (18) | |||||||
Expression_cluster (95) | |||||||
Interaction (23) | |||||||
Map_info | Map | II | Position | 1.15927 | Error | 0.011529 | |
Positive | Positive_clone | D2013 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00029101 | ||||||
WBPaper00030935 | |||||||
WBPaper00038491 | |||||||
WBPaper00041898 | |||||||
WBPaper00055090 | |||||||
WBPaper00058949 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |