WormBase Tree Display for Gene: WBGene00004274
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| WBGene00004274 | SMap | S_parent | Sequence | F53G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rab-11.1 | Person_evidence | WBPerson451 | |||||
| Sequence_name | F53G12.1 | ||||||||
| Molecular_name | F53G12.1 | ||||||||
| F53G12.1.1 | |||||||||
| CE11006 | |||||||||
| Other_name | rab-11 | Paper_evidence | WBPaper00034709 | ||||||
| CELE_F53G12.1 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | rab-11.1 | ||||||||
| DB_info | Database | AceView | gene | 1A582 | |||||
| WormQTL | gene | WBGene00004274 | |||||||
| WormFlux | gene | WBGene00004274 | |||||||
| NDB | locus_tag | CELE_F53G12.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004274|UniProtKB=O01803 | |||||||
| family | PTHR47979 | ||||||||
| NCBI | gene | 171601 | |||||||
| RefSeq | protein | NM_058274.6 | |||||||
| SwissProt | UniProtAcc | O01803 | |||||||
| TREEFAM | TREEFAM_ID | TF300099 | |||||||
| UniProt_GCRP | UniProtAcc | O01803 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rab | ||||||||
| Allele (49) | |||||||||
| Strain | WBStrain00040386 | ||||||||
| WBStrain00040387 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (37) | |||||||||
| Contained_in_operon | CEOP1957 | ||||||||
| Ortholog (43) | |||||||||
| Paralog (32) | |||||||||
| Structured_description | Concise_description | rab-11.1 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; RAB-11.1 activity is required for completion of the final stages of cytokinesis during early embryogenesis and for efficient uptake of yolk proteins during oocyte development; RAB-11.1 is also required for normal peripheral localization of nuclei in the synctial germ cell in the ovary and for regulated secretion of CAV-1-containing cortical granules following fertilization; RAB-11.1 localizes to recycling endosomes and to cortical granules. | Paper_evidence | WBPaper00003831 | |||||
| WBPaper00004697 | |||||||||
| WBPaper00027018 | |||||||||
| WBPaper00032152 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Feb 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable GTP binding activity and GTPase activity. Involved in several processes, including eggshell formation; membrane addition at site of mitotic cytokinesis; and vesicle-mediated transport. Located in Golgi trans cisterna membrane; cortical granule; and recycling endosome. Expressed in gonad. Is an ortholog of human RAB11A (RAB11A, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F53G12.1 | |||||||
| Corresponding_transcript | F53G12.1.1 | ||||||||
| Other_sequence (124) | |||||||||
| Associated_feature | WBsf648892 | ||||||||
| WBsf663857 | |||||||||
| WBsf663858 | |||||||||
| WBsf218867 | |||||||||
| WBsf218868 | |||||||||
| WBsf218869 | |||||||||
| WBsf218870 | |||||||||
| WBsf218871 | |||||||||
| Experimental_info | RNAi_result (31) | ||||||||
| Expr_pattern | Expr4018 | ||||||||
| Expr4949 | |||||||||
| Expr8340 | |||||||||
| Expr8341 | |||||||||
| Expr8956 | |||||||||
| Expr1022979 | |||||||||
| Expr1032113 | |||||||||
| Expr1151979 | |||||||||
| Expr2015214 | |||||||||
| Expr2033448 | |||||||||
| Drives_construct | WBCnstr00012362 | ||||||||
| Construct_product (24) | |||||||||
| Antibody | WBAntibody00001208 | ||||||||
| WBAntibody00001396 | |||||||||
| WBAntibody00001957 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (145) | |||||||||
| Interaction (110) | |||||||||
| Map_info | Map | I | Position | -19.8403 | Error | 0.203444 | |||
| Positive | Positive_clone | F53G12 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5490 | |||||||
| Pseudo_map_position | |||||||||
| Reference (42) | |||||||||
| Remark | Sequence connection from [Kuwabara PE] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
