WormBase Tree Display for Gene: WBGene00004256

WBGene00004256 Evidence: Person_evidence: WBPerson345
  SMap: S_parent: Sequence: ZK994
  Identity: Version: 2
    Name: CGC_name: pxn-1 Person_evidence: WBPerson345
      Sequence_name: ZK994.3
      Molecular_name: ZK994.3
        ZK994.3.1
        CE40298
      Other_name: CELE_ZK994.3 Accession_evidence: NDB BX284605
      Public_name: pxn-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 26 May 2006 16:35:34 WBPerson1849 Event: Acquires_merge: WBGene00022841
      Acquires_merge: WBGene00022841
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pxn
    Allele (85)
    Strain: WBStrain00031626
      WBStrain00050780
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (55)
    Paralog: WBGene00004257 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009897 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00022743 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00015841 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017968 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019970 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00008627 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019613 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00016700 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00011530 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable peroxidase activity. Involved in muscle attachment and positive regulation of axon guidance. Located in basement membrane. Expressed in several structures, including egg-laying apparatus; excretory cell; intestine; somatic nervous system; and spermathecal-uterine valve cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; asthma (multiple); kidney failure (multiple); and lung disease (multiple). Is an ortholog of human PXDN (peroxidasin) and PXDNL (peroxidasin like). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (21)
  Molecular_info: Corresponding_CDS: ZK994.3
    Corresponding_CDS_history: ZK994.3:wp112
      ZK994.3:wp159
    Corresponding_transcript: ZK994.3.1
    Other_sequence (12)
    Associated_feature (18)
  Experimental_info: RNAi_result (6)
    Expr_pattern: Expr12146
      Expr12147
      Expr1018057
      Expr1032099
      Expr1163304
      Expr2015200
      Expr2033434
    Drives_construct: WBCnstr00020277
      WBCnstr00020279
      WBCnstr00035607
    Construct_product: WBCnstr00020279
      WBCnstr00035607
    Microarray_results: SMD_ZK994.3
      SMD_ZK994.4
      182740_at
      188711_at
      A_12_P102222
      A_12_P110849
      GPL13394_WBGene00004256
      GPL13914_ZK994.3
      GPL14144_ZK994.3_2954-3013_0.848_35_C
      GPL14144_ZK994.3_3261-3320_0.662_324_A
      GPL14144_ZK994.3_3432-3491_0.900_11_B
      GPL19516_CGZ0057914
      GPL21109_ZK994.3
      GPL3518_CE15487
      GPL3518_CE15489
      GPL8304_CE_WBGene00004256_A
      GPL8304_CE_WBGene00004256_B
      GPL8673_ZK994_3P02362
      GPL8673_ZK994_3P03125
      GPL8673_ZK994_3P03708
      GPL9450_ZK994.3
      GPL9450_ZK994.4
      cea2.i.49414
      cea2.i.49420
    Expression_cluster (163)
    Interaction (49)
  Map_info: Map: V Position: 1.43195 Error: 0.002031
    Positive: Positive_clone: ZK994 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4596
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene