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WormBase Tree Display for Gene: WBGene00004204

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Name Class

WBGene00004204SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion2
NameCGC_nameswsn-4Person_evidenceWBPerson552
WBPerson407
Sequence_nameF01G4.1
Molecular_nameF01G4.1
F01G4.1.1
CE05553
Other_namepsa-4Person_evidenceWBPerson552
CELE_F01G4.1Accession_evidenceNDBBX284604
Public_nameswsn-4
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
211 Feb 2011 15:17:24WBPerson2970Name_changeCGC_nameswsn-4
Other_namepsa-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classswsn
Allele (50)
StrainWBStrain00001167
WBStrain00001676
WBStrain00001677
WBStrain00031323
WBStrain00008467
WBStrain00048602
WBStrain00054726
RNASeq_FPKM (74)
GO_annotation (18)
Contained_in_operonCEOP4412
Ortholog (67)
Paralog (20)
Structured_descriptionConcise_descriptionswsn-4 (phasmid socket absent) gene encodes an ortholog of SWI2/SNF2, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; swsn-4 is probably required during mitosis of the T cells for asymmetric cell division.Paper_evidenceWBPaper00004350
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated01 Aug 2011 00:00:00
Automated_descriptionPredicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Involved in gonad development. Predicted to be located in nucleus. Expressed in several structures, including head; hyp7 syncytium; tail; ventral cord neurons; and vulval cell. Used to study alcohol use disorder and cancer. Human ortholog(s) of this gene implicated in several diseases, including Coffin-Siris syndrome 4; carcinoma (multiple); and rhabdoid cancer. Is an ortholog of human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) and SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:162Homo sapiensPaper_evidenceWBPaper00060275
Curator_confirmedWBPerson324
Date_last_updated28 Jul 2022 00:00:00
DOID:1574Homo sapiensPaper_evidenceWBPaper00046494
Curator_confirmedWBPerson324
Date_last_updated20 May 2019 00:00:00
Potential_modelDOID:0070046Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11100)
DOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11100)
DOID:10283Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11098,HGNC:11100)
DOID:3672Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11100)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11100)
Models_disease_in_annotationWBDOannot00001297
Models_disease_assertedWBDOannot00000663
Molecular_infoCorresponding_CDSF01G4.1
Corresponding_transcriptF01G4.1.1
Other_sequence (109)
Associated_feature (14)
Transcription_factorWBTranscriptionFactor000378
Experimental_infoRNAi_result (14)
Expr_pattern (12)
Drives_constructWBCnstr00002059
WBCnstr00004205
WBCnstr00009748
WBCnstr00010070
WBCnstr00037928
WBCnstr00038385
Construct_productWBCnstr00010070
WBCnstr00037928
WBCnstr00038385
Microarray_results (21)
Expression_cluster (199)
Interaction (369)
Map_infoMapIVPosition4.90728Error0.003105
PositivePositive_cloneF01G4Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4526
4609
Pseudo_map_position
Reference (19)
RemarkSequence connection from [Goldstein B], [020620 krb]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene