WormBase Tree Display for Gene: WBGene00004191

WBGene00004191 SMap: S_parent: Sequence: C11H1
  Identity: Version: 1
    Name: CGC_name: prx-1
      Sequence_name: C11H1.4
      Molecular_name: C11H1.4a
        C11H1.4a.1
        CE30339
        C11H1.4b
        CE05265
        C11H1.4b.1
      Other_name: pex-1 Paper_evidence: WBPaper00004835
            WBPaper00018161
            WBPaper00005418
            WBPaper00005877
        pex1 Accession_evidence: EMBL AB054992
        C11H1.6 Paper_evidence: WBPaper00005418
        CELE_C11H1.4 Accession_evidence: NDB BX284606
      Public_name: prx-1
    DB_info: Database: WormQTL gene WBGene00004191
        WormFlux gene WBGene00004191
        NDB locus_tag CELE_C11H1.4
        Panther gene CAEEL|WormBase=WBGene00004191|UniProtKB=G5ED99
          family PTHR23077
        NCBI gene 181538
        RefSeq protein NM_001381145.1
            NM_077985.7
        TREEFAM TREEFAM_ID TF106447
        TrEMBL UniProtAcc G5ED99
            A6ZJ67
        UniProt_GCRP UniProtAcc G5ED99
        OMIM gene 602136
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: prx
    Allele (302)
    Strain: WBStrain00035803
    RNASeq_FPKM (74)
    GO_annotation: 00005027
      00005028
      00005029
      00005030
      00005031
      00005032
      00112456
      00112457
      00112458
      00112459
    Ortholog (35)
    Paralog: WBGene00003119 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007352 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00008053 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00004195 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010562 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013156 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: prx-1 encodes a predicted peroxin, a subfamily 2 member of the AAA (ATPases Associated with diverse cellular Activities) family that affects growth in one large-scale RNAi screen; expressed in intestinal cells throughout development. Paper_evidence: WBPaper00004835
            WBPaper00006395
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable ATP hydrolysis activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Is an ortholog of human PEX1 (peroxisomal biogenesis factor 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080623 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8850)
      DOID:0080476 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8850)
      DOID:0081240 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:8850)
  Molecular_info: Corresponding_CDS: C11H1.4a
      C11H1.4b
    Corresponding_CDS_history: C11H1.4:wp74
    Corresponding_transcript: C11H1.4a.1
      C11H1.4b.1
    Other_sequence (19)
    Associated_feature (18)
  Experimental_info: RNAi_result: WBRNAi00028813 Inferred_automatically: RNAi_primary
      WBRNAi00062860 Inferred_automatically: RNAi_primary
      WBRNAi00040366 Inferred_automatically: RNAi_primary
      WBRNAi00024539 Inferred_automatically: RNAi_primary
      WBRNAi00040365 Inferred_automatically: RNAi_primary
      WBRNAi00024538 Inferred_automatically: RNAi_primary
      WBRNAi00010633 Inferred_automatically: RNAi_primary
      WBRNAi00027170 Inferred_automatically: RNAi_primary
      WBRNAi00010631 Inferred_automatically: RNAi_primary
      WBRNAi00007234 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1637
      Expr1022255
      Expr1032051
      Expr1144429
      Expr2015124
      Expr2033362
    Microarray_results (25)
    Expression_cluster (82)
    Interaction (72)
  Map_info: Map: X Position: 16.6804 Error: 0.001645
    Positive: Positive_clone: C11H1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4254
        4606
        5538
    Pseudo_map_position
  Reference (12)
  Remark: Sequence connection from [Motley AM, Plasterk RHA], 02/06/13 krb.
    The connected sequence (C11H1.4) was previously C11H1.6 (the C11H1.4 gene was extended and incorporated C11H1.6). krb
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene