WormBase Tree Display for Gene: WBGene00004185
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| WBGene00004185 | SMap | S_parent | Sequence | R166 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pro-1 | Person_evidence | WBPerson275 | |||||
| Sequence_name | R166.4 | ||||||||
| Molecular_name | R166.4 | ||||||||
| R166.4.1 | |||||||||
| CE03583 | |||||||||
| Other_name | CELE_R166.4 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | pro-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pro | ||||||||
| Allele (45) | |||||||||
| Strain | WBStrain00007707 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Contained_in_operon | CEOP2492 | ||||||||
| Ortholog (32) | |||||||||
| Structured_description | Concise_description | pro-1 encodes a WD-repeat-containing protein that is orthologous to Saccharomyces cerevisiae IPI3; pro-1 activity is required for ribosome biogenesis and specifically, for efficient processing of intervening sequence 2 (ITS2) from rRNA intermediates during 26S rRNA maturation; during development, pro-1 is essential for larval growth, fertility, and normal cell division patterns; in addition, pro-1 is required cell autonomously in the somatic gonad for proper spatial and temporal regulation of germline development and proliferation; a pro-1 promoter::gfp fusion construct reveals that pro-1 is widely expressed in the embryo as well as in every major post-embryonic lineage including the somatic gonad. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00006395 | |||||||||
| WBPaper00006484 | |||||||||
| WBPaper00028280 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 01 Aug 2006 00:00:00 | ||||||||
| Automated_description | Involved in germ cell development; gonad development; and rRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of Rix1 complex and nuclear pre-replicative complex. Expressed widely. Is an ortholog of human WDR18 (WD repeat domain 18). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R166.4 | |||||||
| Corresponding_transcript | R166.4.1 | ||||||||
| Other_sequence (37) | |||||||||
| Associated_feature | WBsf650505 | ||||||||
| WBsf989377 | |||||||||
| WBsf989378 | |||||||||
| WBsf223807 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Expr2932 | ||||||||
| Expr1021028 | |||||||||
| Expr1032045 | |||||||||
| Expr1155642 | |||||||||
| Expr2015103 | |||||||||
| Expr2033341 | |||||||||
| Drives_construct | WBCnstr00001236 | ||||||||
| WBCnstr00011026 | |||||||||
| WBCnstr00035649 | |||||||||
| Construct_product | WBCnstr00011026 | ||||||||
| WBCnstr00035649 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (107) | |||||||||
| Interaction (79) | |||||||||
| Map_info | Positive | Positive_clone | R166 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Mapping_data | Multi_point | 4771 | |||||||
| 4772 | |||||||||
| 4773 | |||||||||
| Pos_neg_data | 10741 | ||||||||
| 10742 | |||||||||
| 10743 | |||||||||
| 10744 | |||||||||
| Interpolated_map_position | II | 3.07684 | |||||||
| Reference (14) | |||||||||
| Method | Gene |
