WormBase Tree Display for Gene: WBGene00004061

WBGene00004061 Evidence: Person_evidence: WBPerson583
      WBPerson36
    CGC_data_submission
  SMap: S_parent: Sequence: C06A12
  Identity: Version: 1
    Name: CGC_name: pmp-4 Person_evidence: WBPerson36
      Sequence_name: T02D1.5
      Molecular_name: T02D1.5
        T02D1.5.1
        CE16325
      Other_name: tag-14 CGC_data_submission
        CELE_T02D1.5 Accession_evidence: NDB BX284604
      Public_name: pmp-4
    DB_info: Database: AceView gene 4S346
        WormQTL gene WBGene00004061
        NDB locus_tag CELE_T02D1.5
        Panther gene CAEEL|WormBase=WBGene00004061|UniProtKB=O45730
          family PTHR11384
        NCBI gene 24104835
        RefSeq protein NM_001306751.3
        TREEFAM TREEFAM_ID TF105205
        TrEMBL UniProtAcc O45730
        UniProt_GCRP UniProtAcc O45730
        OMIM gene 300371
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pmp
    Allele (108)
    Strain: WBStrain00001302
      WBStrain00031414
      WBStrain00035573
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog: WBGene00069534 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00023782 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00145705 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00101152 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00128520 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00231879 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g11392 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3958 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g16340 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g9131 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g11445 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g26590 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g15766 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g314 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g26375 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g7207 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00515.g11743 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_12260.g23647 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-pmp-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold70.g413 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01130.g18623 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_19505 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_011978 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02851 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g20447 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40215000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12901 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00212424 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00242248 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00267184 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00296147 Trichuris muris From_analysis: WormBase-Compara
      WBGene00302384 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001671 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            OMA
            OrthoFinder
            Panther
            PhylomeDB
      SGD:S000006068 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0039890 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050517-27 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:61 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:66 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1349215 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1349467 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:69244 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1562128 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00004058 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004059 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004060 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004062 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: The pmp-4 gene encodes a homolog of human ALD, which when mutated leads to X-linked adrenoleukodystrophy (OMIM:300100). Paper_evidence: WBPaper00004103
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Used to study adrenoleukodystrophy. Human ortholog(s) of this gene implicated in adrenoleukodystrophy. Is an ortholog of human ABCD1 (ATP binding cassette subfamily D member 1) and ABCD2 (ATP binding cassette subfamily D member 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:10588 Homo sapiens Paper_evidence: WBPaper00059252
          Curator_confirmed: WBPerson324
          Date_last_updated: 04 Jan 2021 00:00:00
    Potential_model: DOID:10588 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:61)
  Models_disease_asserted: WBDOannot00000840
    WBDOannot00000841
  Molecular_info: Corresponding_CDS: T02D1.5
    Corresponding_transcript: T02D1.5.1
    Other_sequence (31)
    Associated_feature: WBsf652423
      WBsf668588
      WBsf717215
  Experimental_info: RNAi_result: WBRNAi00018023 Inferred_automatically: RNAi_primary
      WBRNAi00002422 Inferred_automatically: RNAi_primary
      WBRNAi00035055 Inferred_automatically: RNAi_primary
      WBRNAi00052205 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6572
      Expr15211
      Expr15212
      Expr15213
      Expr1018172
      Expr1031959
      Expr1155835
      Expr2014975
      Expr2033210
    Drives_construct: WBCnstr00002195
      WBCnstr00035715
      WBCnstr00042070
      WBCnstr00042071
      WBCnstr00042089
    Construct_product: WBCnstr00035715
      WBCnstr00042071
      WBCnstr00042089
    Antibody: WBAntibody00002912
    Microarray_results (22)
    Expression_cluster (164)
    Interaction (100)
  Map_info: Map: IV Position: 16.8463 Error: 0.037163
    Positive: Positive_clone: T02D1 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4778
        4901
    Pseudo_map_position
  Reference: WBPaper00016821
    WBPaper00027644
    WBPaper00031484
    WBPaper00038491
    WBPaper00047097
    WBPaper00055090
    WBPaper00059252
    WBPaper00060821
    WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene