WormBase Tree Display for Gene: WBGene00004052
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WBGene00004052 | SMap | S_parent | Sequence | H23L24 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name (5) | |||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 18 Nov 2014 11:51:19 | WBPerson2970 | Name_change | CGC_name | parg-2 | ||||
Other_name | pme-4 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | parg | ||||||||
Allele (43) | |||||||||
Strain | WBStrain00035943 | ||||||||
WBStrain00047360 | |||||||||
WBStrain00047361 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (22) | |||||||||
Ortholog (41) | |||||||||
Paralog | WBGene00004051 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Inparanoid_8 | |||||||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | parg-2 (formerly known as pme-4) encodes a poly(ADP-ribose) glycohydrolase (PARG) orthologous to human PARG (OMIM:603501) and paralogous to PARG-1; PARG-2 exhibits poly(ADP-ribose) glycohydrolase activity in vitro, and is required in vivo for normal resistance to ionizing radiation; PARG-2 is primarily expressed in the cytoplasm of nerve cells in the head and tail, and also in embryos; neuronal expression of PARG-2 may reflect a requirement for PARG in preventing neurodegeneration like that seen in Drosophila. | Paper_evidence | WBPaper00005600 | |||||
WBPaper00028953 | |||||||||
WBPaper00029104 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 14 Nov 2014 00:00:00 | ||||||||
Automated_description | Enables poly(ADP-ribose) glycohydrolase activity. Involved in nucleotide-sugar metabolic process and response to gamma radiation. Located in cytoplasm. Expressed in head neurons and tail neurons. Is an ortholog of human BPHL (biphenyl hydrolase like) and PARG (poly(ADP-ribose) glycohydrolase). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | H23L24.5 | |||||||
Corresponding_CDS_history | H23L24.5:wp90 | ||||||||
Corresponding_transcript | H23L24.5.1 | ||||||||
Associated_feature | WBsf668121 | ||||||||
WBsf230456 | |||||||||
Experimental_info | RNAi_result | WBRNAi00013332 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00033743 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00016298 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00065517 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00049464 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00065516 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00102083 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr4510 | ||||||||
Expr1016211 | |||||||||
Expr1153191 | |||||||||
Expr2014733 | |||||||||
Expr2032967 | |||||||||
Drives_construct | WBCnstr00004939 | ||||||||
WBCnstr00037944 | |||||||||
Construct_product | WBCnstr00037944 | ||||||||
Microarray_results (17) | |||||||||
Expression_cluster (263) | |||||||||
Interaction | WBInteraction000253282 | ||||||||
WBInteraction000580252 | |||||||||
Map_info | Map | IV | Position | 3.95647 | Error | 0.001836 | |||
Positive | Positive_clone | H23L24 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4592 | |||||||
4940 | |||||||||
Pseudo_map_position | |||||||||
Reference (11) | |||||||||
Remark | Sequence connection via email from [Desnoyers S], [krb 020729] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |