WormBase Tree Display for Gene: WBGene00004010
expand all nodes | collapse all nodes | view schema
| WBGene00004010 | SMap | S_parent | Sequence | CHROMOSOME_III | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | pha-1 | Person_evidence | WBPerson561 | |||||
| Sequence_name | Y48A6C.5 | ||||||||
| Molecular_name | Y48A6C.5a | ||||||||
| Y48A6C.5a.1 | |||||||||
| CE22115 | |||||||||
| Y48A6C.5b | |||||||||
| CE34124 | |||||||||
| Y48A6C.5b.1 | |||||||||
| Other_name | pha1 | Accession_evidence | EMBL | X73845 | |||||
| CELE_Y48A6C.5 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | pha-1 | ||||||||
| DB_info | Database | AceView | gene | 3M225 | |||||
| WormQTL | gene | WBGene00004010 | |||||||
| WormFlux | gene | WBGene00004010 | |||||||
| NDB | locus_tag | CELE_Y48A6C.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004010|UniProtKB=G5EGL5 | |||||||
| family | PTHR11929 | ||||||||
| NCBI | gene | 176543 | |||||||
| RefSeq | protein | NM_001027720.3 | |||||||
| NM_001027719.5 | |||||||||
| TREEFAM | TREEFAM_ID | TF322298 | |||||||
| TrEMBL | UniProtAcc | G5EGL5 | |||||||
| Q7YXC4 | |||||||||
| UniProt_GCRP | UniProtAcc | G5EGL5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pha | ||||||||
| Allele (70) | |||||||||
| Legacy_information | See also e2123, e2275, e2286, e2468 | ||||||||
| [C.elegansII] e2123ts : at 25C zygotic embryonic lethal, pharynx fails to undergo late differentiation and morphogenesis; early pharynx development normal. OA>5: e2468 (unconditional), t1001ts,e2286 (weak, 38% hatch and arrest), t1002 (weak,some survival to late larval arrest), etc.See also extragenic suppressors sup-35, sup-36, sup-37. Cloned: 2.2kb embryonic transcript, encodes 491 aa predicted protein with some similarity to bZIP transcription factors; pha-1:lacZ expressed transiently in all pharyngeal precursor cells. [Granato et al. 1994; GE] | |||||||||
| Strain (593) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (20) | |||||||||
| Paralog (14) | |||||||||
| Structured_description | Concise_description | pha-1 encodes a novel protein that contains a DUF1114 domain of unknown function found in a number of other nematode proteins; during embryonic development, pha-1 functions redundantly with class B SynMuv genes such as lin-35/Rb and efl-1 to effect pharyngeal morphogenesis; in regulating pharyngeal development, PHA-1 also appears to act with the UBC-18 ubiquitin conjugating enzyme; a PHA-1::GFP reporter is broadly expressed during embryonic development and localizes to the cytoplasm; expression is also observed in early- and late-larval-stage animals, as well as adults, although postembryonic expression is generally weaker than that seen in the embryo. | Paper_evidence | WBPaper00001348 | |||||
| WBPaper00002047 | |||||||||
| WBPaper00024215 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 02 Jul 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable alpha-(1->3)-fucosyltransferase activity. Involved in embryonic digestive tract morphogenesis; nematode larval development; and reproduction. Located in cytoplasm. Expressed in body wall muscle cell and pharynx. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y48A6C.5a | |||||||
| Y48A6C.5b | |||||||||
| Corresponding_transcript | Y48A6C.5a.1 | ||||||||
| Y48A6C.5b.1 | |||||||||
| Other_sequence | X73845 | ||||||||
| Associated_feature | WBsf994278 | ||||||||
| WBsf994279 | |||||||||
| WBsf1015931 | |||||||||
| WBsf1015932 | |||||||||
| WBsf225796 | |||||||||
| WBsf225797 | |||||||||
| Transcription_factor | WBTranscriptionFactor000527 | ||||||||
| Experimental_info | RNAi_result (34) | ||||||||
| Expr_pattern | Expr1579 | ||||||||
| Expr2985 | |||||||||
| Expr1025653 | |||||||||
| Expr1031918 | |||||||||
| Expr1160324 | |||||||||
| Expr2014879 | |||||||||
| Expr2033114 | |||||||||
| Drives_construct | WBCnstr00000210 | ||||||||
| WBCnstr00000211 | |||||||||
| WBCnstr00000212 | |||||||||
| WBCnstr00010343 | |||||||||
| WBCnstr00011064 | |||||||||
| WBCnstr00014859 | |||||||||
| WBCnstr00018920 | |||||||||
| WBCnstr00019419 | |||||||||
| WBCnstr00022365 | |||||||||
| Construct_product (13) | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (69) | |||||||||
| Interaction (57) | |||||||||
| Map_info | Map | III | Position | 6.14398 | Error | 0.074527 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | tDf1 | |||||||
| tDp1 | |||||||||
| tDp2 | |||||||||
| Positive_clone | CB#H8J04 | ||||||||
| Y48A6C | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | Multi_point | 1248 | |||||||
| 1249 | |||||||||
| 2786 | |||||||||
| 4392 | |||||||||
| Pos_neg_data | 5729 | ||||||||
| 5738 | |||||||||
| 5949 | |||||||||
| 8415 | |||||||||
| Reference (95) | |||||||||
| Method | Gene |
