Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00004010

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00004010SMapS_parentSequenceCHROMOSOME_III
IdentityVersion1
NameCGC_namepha-1Person_evidenceWBPerson561
Sequence_nameY48A6C.5
Molecular_nameY48A6C.5a
Y48A6C.5a.1
CE22115
Y48A6C.5b
CE34124
Y48A6C.5b.1
Other_namepha1Accession_evidenceEMBLX73845
CELE_Y48A6C.5Accession_evidenceNDBBX284603
Public_namepha-1
DB_infoDatabaseAceViewgene3M225
WormQTLgeneWBGene00004010
WormFluxgeneWBGene00004010
NDBlocus_tagCELE_Y48A6C.5
PanthergeneCAEEL|WormBase=WBGene00004010|UniProtKB=G5EGL5
familyPTHR11929
NCBIgene176543
RefSeqproteinNM_001027720.3
NM_001027719.5
TREEFAMTREEFAM_IDTF322298
TrEMBLUniProtAccG5EGL5
Q7YXC4
UniProt_GCRPUniProtAccG5EGL5
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpha
Allele (70)
Legacy_informationSee also e2123, e2275, e2286, e2468
[C.elegansII] e2123ts : at 25C zygotic embryonic lethal, pharynx fails to undergo late differentiation and morphogenesis; early pharynx development normal. OA>5: e2468 (unconditional), t1001ts,e2286 (weak, 38% hatch and arrest), t1002 (weak,some survival to late larval arrest), etc.See also extragenic suppressors sup-35, sup-36, sup-37. Cloned: 2.2kb embryonic transcript, encodes 491 aa predicted protein with some similarity to bZIP transcription factors; pha-1:lacZ expressed transiently in all pharyngeal precursor cells. [Granato et al. 1994; GE]
Strain (593)
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (20)
Paralog (14)
Structured_descriptionConcise_descriptionpha-1 encodes a novel protein that contains a DUF1114 domain of unknown function found in a number of other nematode proteins; during embryonic development, pha-1 functions redundantly with class B SynMuv genes such as lin-35/Rb and efl-1 to effect pharyngeal morphogenesis; in regulating pharyngeal development, PHA-1 also appears to act with the UBC-18 ubiquitin conjugating enzyme; a PHA-1::GFP reporter is broadly expressed during embryonic development and localizes to the cytoplasm; expression is also observed in early- and late-larval-stage animals, as well as adults, although postembryonic expression is generally weaker than that seen in the embryo.Paper_evidenceWBPaper00001348
WBPaper00002047
WBPaper00024215
Curator_confirmedWBPerson1843
Date_last_updated02 Jul 2007 00:00:00
Automated_descriptionPredicted to enable alpha-(1->3)-fucosyltransferase activity. Involved in embryonic digestive tract morphogenesis; nematode larval development; and reproduction. Located in cytoplasm. Expressed in body wall muscle cell and pharynx.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY48A6C.5a
Y48A6C.5b
Corresponding_transcriptY48A6C.5a.1
Y48A6C.5b.1
Other_sequenceX73845
Associated_featureWBsf994278
WBsf994279
WBsf1015931
WBsf1015932
WBsf225796
WBsf225797
Transcription_factorWBTranscriptionFactor000527
Experimental_infoRNAi_result (34)
Expr_patternExpr1579
Expr2985
Expr1025653
Expr1031918
Expr1160324
Expr2014879
Expr2033114
Drives_constructWBCnstr00000210
WBCnstr00000211
WBCnstr00000212
WBCnstr00010343
WBCnstr00011064
WBCnstr00014859
WBCnstr00018920
WBCnstr00019419
WBCnstr00022365
Construct_product (13)
Microarray_results (23)
Expression_cluster (69)
Interaction (57)
Map_infoMapIIIPosition6.14398Error0.074527
Well_ordered
PositiveInside_rearrtDf1
tDp1
tDp2
Positive_cloneCB#H8J04
Y48A6CInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point1248
1249
2786
4392
Pos_neg_data5729
5738
5949
8415
ReferenceWBPaper00001009
WBPaper00001348
WBPaper00001437
WBPaper00001571
WBPaper00001654
WBPaper00001687
WBPaper00001722
WBPaper00001725
WBPaper00001781
WBPaper00001961
WBPaper00002047
WBPaper00002877
WBPaper00002925
WBPaper00003068
WBPaper00003170
WBPaper00003797
WBPaper00004244
WBPaper00004352
WBPaper00004964
WBPaper00005423
WBPaper00005463
WBPaper00005870
WBPaper00011072
WBPaper00012630
WBPaper00013995
WBPaper00014320
WBPaper00014321
WBPaper00015309
WBPaper00015760
WBPaper00017530
WBPaper00017688
WBPaper00017768
WBPaper00018108
WBPaper00019458
WBPaper00019596
WBPaper00022015
WBPaper00022049
WBPaper00022053
WBPaper00022245
WBPaper00022378
WBPaper00022417
WBPaper00022560
WBPaper00024012
WBPaper00024013
WBPaper00024017
WBPaper00024134
WBPaper00024215
WBPaper00024333
WBPaper00024823
WBPaper00025247
WBPaper00026062
WBPaper00026224
WBPaper00026338
WBPaper00027075
WBPaper00027135
WBPaper00027309
WBPaper00027311
WBPaper00027319
WBPaper00027514
WBPaper00029013
WBPaper00029033
WBPaper00030666
WBPaper00030736
WBPaper00032000
WBPaper00032175
WBPaper00033189
WBPaper00033464
WBPaper00033469
WBPaper00034110
WBPaper00034475
WBPaper00034803
WBPaper00038632
WBPaper00040976
WBPaper00041001
WBPaper00041549
WBPaper00042703
WBPaper00042744
WBPaper00044385
WBPaper00045462
WBPaper00051222
WBPaper00052065
WBPaper00053062
WBPaper00053706
WBPaper00056672
WBPaper00057783
WBPaper00059440
WBPaper00059520
WBPaper00060014
WBPaper00060799
WBPaper00062568
WBPaper00064376
WBPaper00064933
WBPaper00065100
WBPaper00065114
WBPaper00065652
MethodGene