WormBase Tree Display for Gene: WBGene00003991

WBGene00003991 Evidence: Person_evidence: WBPerson463
  SMap: S_parent: Sequence: K03E6
  Identity: Version: 1
    Name: CGC_name: pfn-3 Person_evidence: WBPerson75
      Sequence_name: K03E6.6
      Molecular_name: K03E6.6
        K03E6.6.1
        CE07332
      Other_name: CELE_K03E6.6 Accession_evidence: NDB BX284606
      Public_name: pfn-3
    DB_info: Database: AceView gene XB698
        WormQTL gene WBGene00003991
        WormFlux gene WBGene00003991
        NDB locus_tag CELE_K03E6.6
        Panther gene CAEEL|WormBase=WBGene00003991|UniProtKB=Q21193
          family PTHR11604
        NCBI gene 180460
        RefSeq protein NM_075804.7
        SwissProt UniProtAcc Q21193
        TREEFAM TREEFAM_ID TF300134
        UniProt_GCRP UniProtAcc Q21193
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pfn
    Allele (29)
    Strain: WBStrain00003252
      WBStrain00029954
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (31)
    Paralog: WBGene00003989 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00003990 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable actin monomer binding activity. Involved in muscle thin filament assembly. Located in striated muscle dense body. Expressed in body wall musculature. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: K03E6.6
    Corresponding_transcript: K03E6.6.1
    Other_sequence (53)
    Associated_feature: WBsf716621
      WBsf1003935
      WBsf1003936
      WBsf1022210
      WBsf1022211
      WBsf236998
      WBsf236999
  Experimental_info: RNAi_result: WBRNAi00098009 Inferred_automatically: RNAi_primary
      WBRNAi00049838 Inferred_automatically: RNAi_primary
      WBRNAi00022831 Inferred_automatically: RNAi_primary
      WBRNAi00033920 Inferred_automatically: RNAi_primary
      WBRNAi00016547 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3807
      Expr3811
      Expr6318
      Expr1014538
      Expr1031907
      Expr1153551
      Expr2014853
      Expr2033088
    Drives_construct: WBCnstr00003727
      WBCnstr00011671
      WBCnstr00035759
    Construct_product: WBCnstr00035759
    Antibody: WBAntibody00001034
    Microarray_results (23)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038213:E.coli(LF82)_72h_downregulated
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00044246:pgrn-1_ced-1_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_upregulated_HeatShock
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_protein
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046121:mesoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:P-granule-RNAi_upregulated_Set1
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048952:glucose_induced
      WBPaper00048988:neuron_expressed
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050053:muscle_enriched_Day12
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_nucleus_expressed
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053615:SMO-1_target
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056284:ints-6(t1903)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00057288:iff-1(RNAi)_upregulated_protein
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_downregulated_L1
      WBPaper00060445:nfki-1(cer1)_downregulated_L1
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060911:prx-5(RNAi)_downregulated_mRNA
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:BWM_anterior
      WBPaper00061340:BWM_far_posterior
      WBPaper00061340:Intestinal_and_rectal_muscle
      WBPaper00061340:mu_int_mu_anal
      WBPaper00061340:mu_sph
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061651:ADF_enriched
      WBPaper00061902:camt-1(ok515)_regulated_AFD
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062520:qui-1(db104)_upregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065392:Lb.rhamnosus_downregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:1_1
      WBPaper00065841:4_1
      WBPaper00065841:7_3
      WBPaper00065841:38_1
      WBPaper00065841:38_3
      WBPaper00065841:143_0
      cgc4386_cluster_3_6
      cgc4489_group_8
      WBPaper00005124:cholesterol_10-9M_regulated
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00032948:FedUp
      WBPaper00034739:N2lessDR1350
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_I
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00037695:LD_3-day
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_prime
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00049311:sAg-MNP_regulated
      WBPaper00050767:Octopamine_induced
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_B
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction (106)
  Map_info: Map: X Position: -18.7365 Error: 0.004034
    Positive: Positive_clone: K03E6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024757
    WBPaper00026958
    WBPaper00027155
    WBPaper00032338
    WBPaper00033099
    WBPaper00038491
    WBPaper00040494
    WBPaper00055090
    WBPaper00057543
    WBPaper00058750
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene