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WormBase Tree Display for Gene: WBGene00003981

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Name Class

WBGene00003981SMapS_parentSequenceF18G5
IdentityVersion1
NameCGC_namepes-8Person_evidenceWBPerson266
Sequence_nameF18G5.2
Molecular_nameF18G5.2a
F18G5.2a.1
CE53188
F18G5.2b
CE53356
F18G5.2b.1
Other_nameCELE_F18G5.2Accession_evidenceNDBBX284606
Public_namepes-8
DB_infoDatabaseAceViewgeneXJ873
WormQTLgeneWBGene00003981
WormFluxgeneWBGene00003981
NDBlocus_tagCELE_F18G5.2
NCBIgene191742
RefSeqproteinNM_001373415.1
NM_001373414.2
TrEMBLUniProtAccA0A4V6M3D6
A0A4V0INE6
UniProt_GCRPUniProtAccA0A4V0INE6
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpes
Allele (72)
Legacy_information[C.elegansII] NMK. pes-8:lacZ expression in 3 rectal epithelial cells from L1 onward, spermatheca from L4, uterus in adult (Ut-1, Ut-2, Use);adult male proctodeum. Clone UL#38E12, cosmid F18G5. [Young and Hope 1993; UL]
RNASeq_FPKM (74)
GO_annotation00003970
Ortholog (23)
Structured_descriptionConcise_descriptionpes-8 encodes a novel protein that contains a proline-rich region and a predicted transmembrane domain, but no otherwise recognizably conserved domains; pes-8 was identified in promoter trapping screens and based on large-scale RNA-mediated interference (RNAi) screens, appears to be required for egg laying, germline development, locomotion, and regulation of adult lifespan; a pes-8 reporter is expressed at the cell surfaces of the spermathecal valve cell, the uterine wall, the vulva, and the rectal epithelium; strong expression is also detected in the uterus during its development; PES-8 may be required for normal morphology of the openings of the spermathecal valve, the vulva, and the rectum, a hypothesis consistent with its expression pattern and RNAi phenotype.Paper_evidenceWBPaper00003306
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be located in membrane. Expressed in hermaphrodite gonad and rectum.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF18G5.2a
F18G5.2b
Corresponding_CDS_historyF18G5.2:wp223
F18G5.2:wp271
Corresponding_transcriptF18G5.2a.1
F18G5.2b.1
Other_sequencePPC02034_1
PP02576
Associated_featureWBsf236141
Experimental_infoRNAi_resultWBRNAi00025139Inferred_automaticallyRNAi_primary
WBRNAi00071839Inferred_automaticallyRNAi_primary
WBRNAi00044967Inferred_automaticallyRNAi_primary
WBRNAi00085555Inferred_automaticallyRNAi_primary
WBRNAi00008662Inferred_automaticallyRNAi_primary
WBRNAi00071625Inferred_automaticallyRNAi_primary
Expr_patternExpr51
Expr1024632
Expr1031901
Expr1148937
Expr2014838
Expr2033073
Drives_constructWBCnstr00035762
Construct_productWBCnstr00035762
Microarray_results (18)
Expression_cluster (227)
Interaction (43)
Map_infoMapXPosition0.940254
PositivePositive_cloneF18G5Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001752
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene