WormBase Tree Display for Gene: WBGene00003925

WBGene00003925 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C36B1
  Identity: Version: 1
    Name: CGC_name: pas-4 Person_evidence: WBPerson1551
      Sequence_name: C36B1.4
      Molecular_name: C36B1.4
        C36B1.4.1
        CE05371
      Other_name: CELE_C36B1.4 Accession_evidence: NDB BX284601
      Public_name: pas-4
    DB_info: Database: AceView gene 1J304
        WormQTL gene WBGene00003925
        WormFlux gene WBGene00003925
        NDB locus_tag CELE_C36B1.4
        Panther gene CAEEL|WormBase=WBGene00003925|UniProtKB=Q95005
          family PTHR11599
        NCBI gene 172679
        RefSeq protein NM_059959.7
        SwissProt UniProtAcc Q95005
        TREEFAM TREEFAM_ID TF106212
        UniProt_GCRP UniProtAcc Q95005
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pas
    Allele (17)
    Strain: WBStrain00002987
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (43)
    Paralog (13)
    Structured_description: Concise_description: pas-4 encodes a proteasome alpha-type seven subunit of the core 20S proteasome subcomplex; loss of pas-4 activity via RNAi results in a wide variety of defects including embryonic and larval lethality, sterility, abnormal locomotion, slow growth, and abnormal transgene expression and subcellular localization; loss of pas-4 activity also results in activation of SKN-1, a transcription factor required in adult worms for the acute response to oxidative stress and maternally for embryonic development. Paper_evidence: WBPaper00004402
            WBPaper00006395
            WBPaper00006510
            WBPaper00024497
            WBPaper00025054
            WBPaper00028383
            WBPaper00030965
          Curator_confirmed: WBPerson1843
          Date_last_updated: 18 Jan 2008 00:00:00
      Automated_description: Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Expressed in tail. Is an ortholog of human PSMA7 (proteasome 20S subunit alpha 7) and PSMA8 (proteasome 20S subunit alpha 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C36B1.4
    Corresponding_transcript: C36B1.4.1
    Other_sequence (94)
    Associated_feature: WBsf649413
      WBsf984491
      WBsf1010268
      WBsf219969
      WBsf219970
  Experimental_info: RNAi_result (25)
    Expr_pattern: Chronogram1931
      Chronogram1944
      Expr5441
      Expr1010437
      Expr1031858
      Expr1146036
      Expr2014743
      Expr2032977
    Drives_construct: WBCnstr00003489
      WBCnstr00035793
    Construct_product: WBCnstr00035793
    Microarray_results (23)
    Expression_cluster (168)
    Interaction (360)
  Map_info: Map: I Position: 3.03696 Error: 0.000521
    Positive: Positive_clone: C36B1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene