WormBase Tree Display for Gene: WBGene00003904
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| WBGene00003904 | Evidence | Author_evidence | Slack FJ | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C17E4 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | pabp-2 | Person_evidence | WBPerson2384 | |||||
| WBPerson599 | |||||||||
| Sequence_name | C17E4.5 | ||||||||
| Molecular_name | C17E4.5 | ||||||||
| C17E4.5.1 | |||||||||
| CE08254 | |||||||||
| Other_name | pab-3 | Person_evidence | WBPerson1160 | ||||||
| CELE_C17E4.5 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | pabp-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 23 Feb 2007 15:37:00 | WBPerson2970 | Name_change | CGC_name | pabp-2 | ||||
| Other_name | pab-3 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pabp | ||||||||
| Allele (19) | |||||||||
| Strain | WBStrain00001368 | ||||||||
| WBStrain00036043 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00085568 | ||||||||
| 00085569 | |||||||||
| 00085570 | |||||||||
| 00085571 | |||||||||
| 00111974 | |||||||||
| 00111975 | |||||||||
| Contained_in_operon | CEOP1543 | ||||||||
| CEOP192 | |||||||||
| Ortholog (48) | |||||||||
| Structured_description | Concise_description | pabp-2 encodes the C. elegans PABPN1 (polyadenylate-binding protein, nuclear 1) ortholog; by homology, PABP-2 is predicted to function as a poly(A)-binding protein involved in several aspects of pre-mRNA processing; large-scale RNAi screens indicate that pabp-2 activity is essential for embryonic and larval development, as well as normal rates of growth and locomotion; in humans, expansion of a polyalanine repeat in PABPN1 is associated with oculopharyngeal muscular dystrophy (OPMD, OMIM:602279). | Paper_evidence | WBPaper00004402 | |||||
| WBPaper00005599 | |||||||||
| WBPaper00006395 | |||||||||
| WBPaper00024497 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00031237 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 27 Nov 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable poly(A) binding activity. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in oculopharyngeal muscular dystrophy. Is an ortholog of human PABPN1 (poly(A) binding protein nuclear 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:11719 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8565) | ||||
| Molecular_info | Corresponding_CDS | C17E4.5 | |||||||
| Corresponding_transcript | C17E4.5.1 | ||||||||
| Other_sequence (45) | |||||||||
| Associated_feature | WBsf976898 | ||||||||
| WBsf220082 | |||||||||
| WBsf220083 | |||||||||
| WBsf220084 | |||||||||
| Experimental_info | RNAi_result (20) | ||||||||
| Expr_pattern | Chronogram862 | ||||||||
| Expr5285 | |||||||||
| Expr1026265 | |||||||||
| Expr1031841 | |||||||||
| Expr1144842 | |||||||||
| Expr2014676 | |||||||||
| Expr2032909 | |||||||||
| Drives_construct | WBCnstr00002258 | ||||||||
| WBCnstr00035805 | |||||||||
| Construct_product | WBCnstr00016328 | ||||||||
| WBCnstr00035805 | |||||||||
| Antibody | WBAntibody00002247 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (121) | |||||||||
| Interaction (116) | |||||||||
| Map_info | Map | I | Position | 3.76033 | Error | 0.000569 | |||
| Positive | Positive_clone | C17E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5225 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027281 | ||||||||
| WBPaper00031006 | |||||||||
| WBPaper00038240 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00048493 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059527 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
