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WormBase Tree Display for Gene: WBGene00003889

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Name Class

WBGene00003889SMapS_parentSequenceB0212
IdentityVersion1
NameCGC_nameosm-9Person_evidenceWBPerson242
Sequence_nameB0212.5
Molecular_nameB0212.5
B0212.5.1
CE20445
Other_namenss-2
CELE_B0212.5Accession_evidenceNDBBX284604
Public_nameosm-9
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classosm
Allele (120)
Legacy_information[C.elegansII] n1601 : defective in osmotic avoidance, also in nose touch avoidance (Not); Adp (partly defective adaptation to isoamyl alcohol and butanone); normal chemotaxis.OA5: n1516, n1603, n2473, ky10 (similar). [Colbert & Bargmann 1995; JT; KP; MT]
StrainWBStrain00023453
WBStrain00036458
WBStrain00005214
WBStrain00007483
WBStrain00052609
RNASeq_FPKM (74)
GO_annotation (33)
Ortholog (45)
ParalogWBGene00003838Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003839Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003840Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00003841Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionosm-9 encodes a TRPV channel homologous to capsaicin receptors; osm-9 is involved in sensory responses to a subset of chemical stimuli and to ASH neuron-mediated osmotic and mechanical stimuli; OSM-9 is also involved in adaptation to volatile odorants and salts; OSM-9 is expressed in a variety of sensory neurons and shows neuron-specific localization to either the cell body or the cilium.Paper_evidenceWBPaper00002166
WBPaper00002930
WBPaper00005150
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated20 Apr 2011 00:00:00
Automated_descriptionEnables calcium channel activity and temperature-gated cation channel activity. Involved in several processes, including heat acclimation; negative adaptation of signaling pathway; and nervous system process. Located in neuronal cell body; non-motile cilium; and perinuclear region of cytoplasm. Expressed in RIG; head mesodermal cell; rectal gland cell; sensory neurons; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); motor neuron disease (multiple); and osteochondrodysplasia (multiple). Is an ortholog of human TRPV3 (transient receptor potential cation channel subfamily V member 3); TRPV4 (transient receptor potential cation channel subfamily V member 4); and TRPV5 (transient receptor potential cation channel subfamily V member 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (17)
Molecular_infoCorresponding_CDSB0212.5
Corresponding_transcriptB0212.5.1
Other_sequence (14)
Associated_featureWBsf667839
WBsf995982
Experimental_infoRNAi_result (14)
Expr_pattern (12)
Drives_constructWBCnstr00000837
WBCnstr00005979
WBCnstr00008561
WBCnstr00010985
WBCnstr00010991
WBCnstr00011000
WBCnstr00011004
WBCnstr00012945
WBCnstr00023098
WBCnstr00035811
Construct_productWBCnstr00000837
WBCnstr00006801
WBCnstr00010991
WBCnstr00011000
WBCnstr00011004
WBCnstr00012945
WBCnstr00020618
WBCnstr00035811
Regulate_expr_clusterWBPaper00049594:osm-9(ok1677)_NaCl(200mM)_upregulate
WBPaper00049594:osm-9(ok1677)_upregulated
Microarray_results (18)
Expression_cluster (103)
Interaction (116)
Anatomy_functionWBbtf0291
WBProcessWBbiopr:00000002
Map_infoMapIVPosition-3.15659Error0.016734
Well_ordered
PositivePositive_cloneB0212Inferred_automaticallyFrom sequence, transcript, pseudogene data
CX#2-12
Mapping_data2_point3729
3730
Multi_point1365
1366
Reference (225)
RemarkPossibly homologous to mammalian capsaicin receptor VR1. Some osm-9 mutants are sensitive to capsaicin.[bionet.celegans from Olsen]Curator_confirmedWBPerson1250
MethodGene