Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00003877

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00003877SMapS_parentSequenceK04E7
IdentityVersion2
NameCGC_namepept-1Person_evidenceWBPerson2603
WBPerson861
Sequence_nameK04E7.2
Molecular_nameK04E7.2
K04E7.2.1
CE25039
Other_namepep-2
opt-2
CELE_K04E7.2Accession_evidenceNDBBX284606
Public_namepept-1
DB_infoDatabaseAceViewgeneXH79
WormQTLgeneWBGene00003877
WormFluxgeneWBGene00003877
NDBlocus_tagCELE_K04E7.2
PanthergeneCAEEL|WormBase=WBGene00003877|UniProtKB=Q21219
familyPTHR11654
NCBIgene180919
RefSeqproteinNM_076686.7
SwissProtUniProtAccQ21219
UniProt_GCRPUniProtAccQ21219
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
229 Apr 2009 13:55:02WBPerson9133Name_changeCGC_namepept-1
Other_nameopt-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpept
AlleleWBVar00088492Inferred_automaticallyFrom strain object: BR2742
WBVar00088496
WBVar01926955
WBVar01498964
WBVar01926956
WBVar02124849
WBVar00249350
WBVar00249351
WBVar01154366
WBVar01154367
WBVar01154368
WBVar01154369
WBVar01154370
WBVar02139448
WBVar02139449
WBVar01154371
WBVar01154372
WBVar01154373
WBVar01154374
WBVar01154375
WBVar01154376
WBVar01154377
WBVar01154378
WBVar01154379
WBVar01154380
WBVar01154381
WBVar01154382
WBVar01154383
WBVar01154384
WBVar01154385
WBVar01154386
WBVar01154387
WBVar01570906
WBVar01154388
WBVar01154389
WBVar01154390
WBVar01154391
WBVar01154392
WBVar01154393
WBVar01154394
WBVar01154395
WBVar00506185
WBVar00506186
WBVar00506187
WBVar00506188
WBVar00506189
WBVar00506190
WBVar00506191
WBVar00506192
WBVar00262297
WBVar00262300
WBVar01526568
WBVar01526569
WBVar01526570
WBVar01526571
WBVar00236053
WBVar00097849
WBVar01550288
WBVar01550289
WBVar01550290
WBVar01945566
WBVar01945567
WBVar01550291
WBVar01550292
WBVar01550293
WBVar01550294
WBVar01550295
WBVar01550296
WBVar01678894
WBVar01469363
WBVar01469364
WBVar00033441
WBVar02083385
WBVar00033451
WBVar00033456
WBVar00033461
WBVar00033466
WBVar00033471
WBVar00033476
WBVar00033481
WBVar00092414
WBVar00603805
WBVar01907875
WBVar00603807
WBVar01500067
Possibly_affected_byWBVar02157263
StrainWBStrain00036075
WBStrain00003894
RNASeq_FPKM (74)
GO_annotation (46)
Ortholog (46)
Paralog (2)
Structured_descriptionConcise_descriptionpept-1 encodes a low affinity/high capacity oligopeptide transporter; pept-1 is required for uptake of intact peptides from the intestine and thus for normal development, growth, and reproduction; genetic studies indicate that pept-1 interacts with both the daf-2/insulin- and let-363/TOR-signaling pathways to regulate lifespan and with the daf-2 pathway to influence stress response; PEPT-1 is expressed in the intestine where it localizes to the apical membrane.Paper_evidenceWBPaper00006186
WBPaper00024423
Curator_confirmedWBPerson1843
Date_last_updated05 Nov 2009 00:00:00
Automated_descriptionEnables dipeptide transmembrane transporter activity. Involved in several processes, including chemical homeostasis; nitrogen compound transport; and regulation of signal transduction. Located in apical plasma membrane. Expressed in intestine. Used to study obesity. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00034742
Curator_confirmedWBPerson324
Date_last_updated15 Sep 2021 00:00:00
Models_disease_assertedWBDOannot00000178
Molecular_infoCorresponding_CDSK04E7.2
Corresponding_transcriptK04E7.2.1
Other_sequence (23)
Associated_featureWBsf662881
WBsf978975
WBsf1005576
WBsf1023101
WBsf235837
Experimental_infoRNAi_result (49)
Expr_patternExpr1421
Expr8048
Expr8049
Expr10732
Expr1026620
Expr1031825
Expr1153607
Expr2014823
Expr2033057
Marker28
Drives_construct (23)
Construct_productWBCnstr00004990
WBCnstr00009194
WBCnstr00013078
WBCnstr00014892
WBCnstr00016252
WBCnstr00018325
WBCnstr00037949
Regulate_expr_clusterWBPaper00045460:Co-expression_Cluster_1
WBPaper00045460:Co-expression_Cluster_2
WBPaper00045460:Co-expression_Cluster_3
WBPaper00045460:pept-1(lg601)_downregulated
WBPaper00045460:pept-1(lg601)_upregulated
AntibodyWBAntibody00002276
Microarray_results (20)
Expression_cluster (236)
Interaction (114)
Map_infoMapXPosition-2.89742Error0.002559
PositivePositive_cloneK04E7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (57)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene