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WormBase Tree Display for Gene: WBGene00003877

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Name Class

WBGene00003877SMapS_parentSequenceK04E7
IdentityVersion2
Name (5)
DB_infoDatabaseAceViewgeneXH79
WormQTLgeneWBGene00003877
WormFluxgeneWBGene00003877
NDBlocus_tagCELE_K04E7.2
PanthergeneCAEEL|WormBase=WBGene00003877|UniProtKB=Q21219
familyPTHR11654
NCBIgene180919
RefSeqproteinNM_076686.7
SwissProtUniProtAccQ21219
UniProt_GCRPUniProtAccQ21219
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
229 Apr 2009 13:55:02WBPerson9133Name_changeCGC_namepept-1
Other_nameopt-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpept
Allele (85)
Possibly_affected_byWBVar02157263
StrainWBStrain00036075
WBStrain00003894
RNASeq_FPKM (74)
GO_annotation (46)
Ortholog (46)
ParalogWBGene00003876Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003878Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionpept-1 encodes a low affinity/high capacity oligopeptide transporter; pept-1 is required for uptake of intact peptides from the intestine and thus for normal development, growth, and reproduction; genetic studies indicate that pept-1 interacts with both the daf-2/insulin- and let-363/TOR-signaling pathways to regulate lifespan and with the daf-2 pathway to influence stress response; PEPT-1 is expressed in the intestine where it localizes to the apical membrane.Paper_evidenceWBPaper00006186
WBPaper00024423
Curator_confirmedWBPerson1843
Date_last_updated05 Nov 2009 00:00:00
Automated_descriptionEnables dipeptide transmembrane transporter activity. Involved in several processes, including chemical homeostasis; nitrogen compound transport; and regulation of signal transduction. Located in apical plasma membrane. Expressed in intestine. Used to study obesity. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00034742
Curator_confirmedWBPerson324
Date_last_updated15 Sep 2021 00:00:00
Models_disease_assertedWBDOannot00000178
Molecular_infoCorresponding_CDSK04E7.2
Corresponding_transcriptK04E7.2.1
Other_sequence (23)
Associated_featureWBsf662881
WBsf978975
WBsf1005576
WBsf1023101
WBsf235837
Experimental_infoRNAi_result (49)
Expr_patternExpr1421
Expr8048
Expr8049
Expr10732
Expr1026620
Expr1031825
Expr1153607
Expr2014823
Expr2033057
Marker28
Drives_construct (23)
Construct_productWBCnstr00004990
WBCnstr00009194
WBCnstr00013078
WBCnstr00014892
WBCnstr00016252
WBCnstr00018325
WBCnstr00037949
Regulate_expr_clusterWBPaper00045460:Co-expression_Cluster_1
WBPaper00045460:Co-expression_Cluster_2
WBPaper00045460:Co-expression_Cluster_3
WBPaper00045460:pept-1(lg601)_downregulated
WBPaper00045460:pept-1(lg601)_upregulated
AntibodyWBAntibody00002276
Microarray_results (20)
Expression_cluster (236)
Interaction (114)
Map_infoMapXPosition-2.89742Error0.002559
PositivePositive_cloneK04E7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00003116
WBPaper00003971
WBPaper00005976
WBPaper00006186
WBPaper00006465
WBPaper00011545
WBPaper00018506
WBPaper00018858
WBPaper00018859
WBPaper00024278
WBPaper00024423
WBPaper00025195
WBPaper00026667
WBPaper00027611
WBPaper00032077
WBPaper00032543
WBPaper00033382
WBPaper00034742
WBPaper00035322
WBPaper00036390
WBPaper00038111
WBPaper00038491
WBPaper00040287
WBPaper00041129
WBPaper00041408
WBPaper00042165
WBPaper00045460
WBPaper00046784
WBPaper00046884
WBPaper00048904
WBPaper00049531
WBPaper00052075
WBPaper00053532
WBPaper00054917
WBPaper00055090
WBPaper00055920
WBPaper00056160
WBPaper00057375
WBPaper00057429
WBPaper00059644
WBPaper00059947
WBPaper00060602
WBPaper00061476
WBPaper00061888
WBPaper00061938
WBPaper00062581
WBPaper00062823
WBPaper00062847
WBPaper00063023
WBPaper00064057
WBPaper00064071
WBPaper00064208
WBPaper00064552
WBPaper00064601
WBPaper00064910
WBPaper00064960
WBPaper00065331
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene