WormBase Tree Display for Gene: WBGene00003877
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WBGene00003877 | SMap | S_parent | Sequence | K04E7 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | pept | |||||
Allele (85) | ||||||
Possibly_affected_by | WBVar02157263 | |||||
Strain | WBStrain00036075 | |||||
WBStrain00003894 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (46) | ||||||
Ortholog (46) | ||||||
Paralog | WBGene00003876 | Caenorhabditis elegans | From_analysis | Panther | ||
WormBase-Compara | ||||||
WBGene00003878 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | ||||||
Structured_description | Concise_description | pept-1 encodes a low affinity/high capacity oligopeptide transporter; pept-1 is required for uptake of intact peptides from the intestine and thus for normal development, growth, and reproduction; genetic studies indicate that pept-1 interacts with both the daf-2/insulin- and let-363/TOR-signaling pathways to regulate lifespan and with the daf-2 pathway to influence stress response; PEPT-1 is expressed in the intestine where it localizes to the apical membrane. | Paper_evidence | WBPaper00006186 | ||
WBPaper00024423 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 05 Nov 2009 00:00:00 | |||||
Automated_description | Enables dipeptide transmembrane transporter activity. Involved in several processes, including chemical homeostasis; nitrogen compound transport; and regulation of signal transduction. Located in apical plasma membrane. Expressed in intestine. Used to study obesity. Is an ortholog of human SLC15A1 (solute carrier family 15 member 1). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00034742 | |
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 15 Sep 2021 00:00:00 | |||||
Models_disease_asserted | WBDOannot00000178 | |||||
Molecular_info | Corresponding_CDS | K04E7.2 | ||||
Corresponding_transcript | K04E7.2.1 | |||||
Other_sequence (23) | ||||||
Associated_feature | WBsf662881 | |||||
WBsf978975 | ||||||
WBsf1005576 | ||||||
WBsf1023101 | ||||||
WBsf235837 | ||||||
Experimental_info | RNAi_result (49) | |||||
Expr_pattern | Expr1421 | |||||
Expr8048 | ||||||
Expr8049 | ||||||
Expr10732 | ||||||
Expr1026620 | ||||||
Expr1031825 | ||||||
Expr1153607 | ||||||
Expr2014823 | ||||||
Expr2033057 | ||||||
Marker28 | ||||||
Drives_construct (23) | ||||||
Construct_product | WBCnstr00004990 | |||||
WBCnstr00009194 | ||||||
WBCnstr00013078 | ||||||
WBCnstr00014892 | ||||||
WBCnstr00016252 | ||||||
WBCnstr00018325 | ||||||
WBCnstr00037949 | ||||||
Regulate_expr_cluster | WBPaper00045460:Co-expression_Cluster_1 | |||||
WBPaper00045460:Co-expression_Cluster_2 | ||||||
WBPaper00045460:Co-expression_Cluster_3 | ||||||
WBPaper00045460:pept-1(lg601)_downregulated | ||||||
WBPaper00045460:pept-1(lg601)_upregulated | ||||||
Antibody | WBAntibody00002276 | |||||
Microarray_results (20) | ||||||
Expression_cluster (236) | ||||||
Interaction (114) | ||||||
Map_info (3) | ||||||
Reference (57) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |