WormBase Tree Display for Gene: WBGene00003701
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| WBGene00003701 | SMap | S_parent | Sequence | F44G3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | nhr-111 | Person_evidence | WBPerson691 | |||||
| Sequence_name | F44G3.9 | ||||||||
| Molecular_name | F44G3.9 | ||||||||
| F44G3.9.1 | |||||||||
| CE35538 | |||||||||
| Other_name | CELE_F44G3.9 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | nhr-111 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nhr | ||||||||
| Laboratory | MU | ||||||||
| Allele (51) | |||||||||
| Strain | WBStrain00031471 | ||||||||
| WBStrain00030117 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (22) | |||||||||
| Paralog (44) | |||||||||
| Structured_description | Concise_description | nhr-111 encodes a member of the nuclear receptor superfamily; by homology, NHR-111 is predicted to function as a ligand-dependent transcriptional regulator, but as loss of nhr-111 activity via large-scale RNAi screens does not result in any abnormalities, the precise role of NHR-111 in C. elegans development and/or behavior is not yet known; an nhr-111 reporter construct is expressed in embryos and early larvae in a pair of neurons in the ventral ganglion of the head and in two cells that may be the somatic gonad precursors. | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00010261 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in PVD; head neurons; intestine; pharynx; and somatic gonad precursor. Human ortholog(s) of this gene implicated in enhanced S-cone syndrome and retinitis pigmentosa 37. Is an ortholog of human NR2E3 (nuclear receptor subfamily 2 group E member 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0090059 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7974) | ||||
| DOID:0110399 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7974) | ||||||
| Molecular_info | Corresponding_CDS | F44G3.9 | |||||||
| Corresponding_CDS_history | F44G3.9:wp109 | ||||||||
| Corresponding_transcript | F44G3.9.1 | ||||||||
| Associated_feature | WBsf653475 | ||||||||
| Transcription_factor | WBTranscriptionFactor000512 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00032265 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00014967 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047336 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076432 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00107731 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr10052 | ||||||||
| Expr1010659 | |||||||||
| Expr1151189 | |||||||||
| Expr1200091 | |||||||||
| Expr2014009 | |||||||||
| Expr2032249 | |||||||||
| Drives_construct | WBCnstr00015024 | ||||||||
| WBCnstr00035933 | |||||||||
| Construct_product | WBCnstr00021796 | ||||||||
| WBCnstr00035933 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (31) | |||||||||
| Interaction (406) | |||||||||
| Map_info | Map | V | Position | 9.74878 | Error | 0.031354 | |||
| Positive | Positive_clone | F44G3 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4529 | |||||||
| 4662 | |||||||||
| 5344 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00010261 | ||||||||
| WBPaper00010476 | |||||||||
| WBPaper00010679 | |||||||||
| WBPaper00018025 | |||||||||
| WBPaper00027309 | |||||||||
| WBPaper00034447 | |||||||||
| WBPaper00041200 | |||||||||
| WBPaper00063946 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
