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WormBase Tree Display for Gene: WBGene00003681

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Name Class

WBGene00003681SMapS_parentSequenceY15E3A
IdentityVersion1
NameCGC_namenhr-91Person_evidenceWBPerson600
Sequence_nameY15E3A.1
Molecular_nameY15E3A.1a
Y15E3A.1a.1
CE27779
Y15E3A.1b
CE38001
Y15E3A.1a.2
Y15E3A.1a.3
Y15E3A.1a.4
Y15E3A.1b.1
Y15E3A.1b.2
Other_nameCELE_Y15E3A.1Accession_evidenceNDBBX284606
Public_namenhr-91
DB_infoDatabaseAceViewgeneXP933
WormQTLgeneWBGene00003681
WormFluxgeneWBGene00003681
NDBlocus_tagCELE_Y15E3A.1
PanthergeneCAEEL|WormBase=WBGene00003681|UniProtKB=Q9U2R6
familyPTHR24083
NCBIgene181621
RefSeqproteinNM_001392897.1
NM_001029782.6
SwissProtUniProtAccQ9U2R6
TREEFAMTREEFAM_IDTF350737
UniProt_GCRPUniProtAccQ9U2R6
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnhr
Allele (95)
RNASeq_FPKM (74)
GO_annotation (19)
Ortholog (35)
Paralog (42)
Structured_descriptionConcise_descriptionnhr-91 encodes a conserved nuclear receptor that is orthologous to members of the NR6 subfamily of nuclear receptors that includes Drosophila HR4 and human germ cell nuclear factor (GCNF, OMIM:600281, human and mouse GCNF are expressed primarily in the testis); by homology, NHR-91 is predicted to function as a transcription factor that may activate or repress transcription in response to a hormonal signal; however, as loss of nhr-91 activity via RNAi does not result in any obvious abnormalities, the precise role of NHR-91 in C. elegans development and/or behavior is not yet known; nhr-91 is expressed in anterior neurons, seam cells, excretory cells, the spermatheca, and the developing vulva.Paper_evidenceWBPaper00005573
WBPaper00006412
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in anterior ganglion; excretory cell; seam cell; spermatheca; and vulva. Is an ortholog of human NR6A1 (nuclear receptor subfamily 6 group A member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY15E3A.1a
Y15E3A.1b
Corresponding_CDS_historyY15E3A.1:wp51
Y15E3A.1:wp138
Corresponding_transcriptY15E3A.1a.1
Y15E3A.1a.2
Y15E3A.1a.3
Y15E3A.1a.4
Y15E3A.1b.1
Y15E3A.1b.2
Other_sequenceES566927.1
EX499800.1
TSC10314_1
JI168333.1
MH04569
MHC02010_1
TSC13709_1
Associated_feature (24)
Transcription_factorWBTranscriptionFactor000197
Experimental_infoRNAi_result (11)
Expr_patternExpr2868
Expr1012698
Expr1031711
Expr1159050
Expr2014243
Expr2032484
Drives_constructWBCnstr00010998
WBCnstr00017594
WBCnstr00017984
WBCnstr00035950
Construct_productWBCnstr00035950
Microarray_results (29)
Expression_clusterWBPaper00032976:non_compensated_genes
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037682:sma-2_upregulated
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00041222:unc-120(st364)_downregulated
WBPaper00044578:reduced-humidity_downregulated_microarray
WBPaper00044736:oscillating_dev_expression
WBPaper00045417:128Q-huntingtin_downreglated
WBPaper00045521:Gender_Neutral
WBPaper00046121:ecdoderm_unique
WBPaper00048611:MnCl2_upregulated
WBPaper00048988:neuron_expressed
WBPaper00049626:UNC-75_target
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050514:CEBP-1_interacting
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00051558:aging_regulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056165:MINA-1_interacting_mRNA
WBPaper00056169:rrf-3(pk1426)_downregulated_L4
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056169:rrf-3(pk1426)_upregulated_L2
WBPaper00056284:ints-1(RNAi)_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056617:adr-1_upregulated_L4_transcript
WBPaper00056826:SGP_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057068:numr-1(RNAi)_downregulated
WBPaper00057347:nhr-14(tm1473)_downreglated
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058691:set-2(bn129)_upregulated
WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
WBPaper00059421:daf-3(mgDf90)_downregulated
WBPaper00059471:EGL-43_interacting
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060273:isp-1(qm150)_upregulated
WBPaper00060445:nfki-1(cer1)_downregulated_L4
WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_downregulated_L4
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061040:FW1256_downregulated
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:ADEsh
WBPaper00061340:CEPso
WBPaper00061340:F_U
WBPaper00061340:ILsh_OLLsh_OLQsh
WBPaper00061340:ILso
WBPaper00061340:Neuroblast_ADE_ADA
WBPaper00061340:Neuroblast_ALM_BDU
WBPaper00061340:Neuroblast_HSN_PHB
WBPaper00061340:Neuroblast_PVC_LUA
WBPaper00061340:PLM_ALN_grandparent
WBPaper00061340:PLM_ALN_great_grandparent
WBPaper00061340:Rectal_cell
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
WBPaper00061466:nath-10(icb102)_downregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061479:ubc-9(ne4833)_upregulated
WBPaper00061527:R07G3.8_9125-ric-4_17408
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062156:jmjd-5(zr1234)_upregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062440:crh-1(n3315)_downregulated
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064532:pals-25(icb98)_downregulated
WBPaper00064721:fasn-1(g14)_downregulated_starved
WBPaper00064871:hypoxia_downregulated_F2
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065746:eat-2(ad1113)_downregulated
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065835:Day11_vs_Day1_upregulated
WBPaper00065841:5_0
WBPaper00065841:80_0
WBPaper00065841:91_0
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066110:tetraploid_vs_diploid_upregulated
cgc4489_group_8
WBPaper00030985:Photorhabdus_luminescens_upregulated
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031252:AIN-2_IP_enriched
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00031832:slr-2_regulated
WBPaper00032948:FedUp
WBPaper00034739:N2lessDR1350
WBPaper00034739:RIL17lessRIL14
WBPaper00035084:L1_enriched_AIN-2_IP
WBPaper00035084:L2_enriched_AIN-2_IP
WBPaper00035084:L3_enriched_AIN-2_IP
WBPaper00035084:L4_enriched_AIN-2_IP
WBPaper00035588:alg-1(-)_upregulated
WBPaper00036130:mir-243_up_regulated
WBPaper00036286:Pattern_G
WBPaper00040185:nhr-23(RNAi)_downregulated
WBPaper00040210:Chlorpyrifos_16C_regulated
WBPaper00040858:eQTL_regulated_old
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00046548:dafachronic-acid_upregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00048989:N2_allantoin_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00055899:nitroguanidine_regulated
[cgc5376]:let-60(G12V)-regulated_genes
Interaction (76)
Map_infoMapXPosition22.4209Error0.024648
PositivePositive_cloneY15E3AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene