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WormBase Tree Display for Gene: WBGene00003607

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Name Class

WBGene00003607EvidencePaper_evidenceWBPaper00003416
WBPaper00004181
SMapS_parentSequenceF33D4
IdentityVersion1
NameCGC_namenhr-8Person_evidenceWBPerson600
Sequence_nameF33D4.1
Molecular_nameF33D4.1a
F33D4.1a.1
CE33927
F33D4.1b
CE33928
F33D4.1b.1
Other_nameCELE_F33D4.1Accession_evidenceNDBBX284604
Public_namenhr-8
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnhr
Allele (42)
Legacy_informationNMK. Nuclear hormone receptor superfamily. [AE]
[C.elegansII] NMK. Nuclear hormone receptor superfamily. YAC Y50A3 etc. [AE]
StrainWBStrain00000059
WBStrain00051691
WBStrain00054632
RNASeq_FPKM (74)
GO_annotation (17)
Ortholog (30)
Paralog (19)
Structured_descriptionConcise_descriptionThe nhr-8 gene encodes a nuclear hormone receptor homolog; nhr-8(ok186) mutants have abnormally low resistance to the toxins colchicine and chloroquine.Paper_evidenceWBPaper00004723
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in cholesterol homeostasis. Located in nucleus. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human VDR (vitamin D receptor).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (53)
Molecular_infoCorresponding_CDSF33D4.1a
F33D4.1b
Corresponding_CDS_historyF33D4.1a:wp99
F33D4.1b:wp99
Corresponding_transcriptF33D4.1a.1
F33D4.1b.1
Other_sequenceOden_contig20559
Oden_isotig10723
DN558166.1
AYC01323_1
HBC03177_1
LSC01052_1
AE02063
ES414143.1
Associated_featureWBsf646108
WBsf646109
WBsf660331
WBsf660332
WBsf978331
WBsf228565
WBsf228566
Transcription_factorWBTranscriptionFactor000264
Experimental_infoRNAi_result (16)
Expr_patternExpr1351
Expr11216
Expr1023140
Expr1031655
Expr1150089
Expr2014241
Expr2032482
Drives_constructWBCnstr00010232
WBCnstr00036006
Construct_productWBCnstr00010232
WBCnstr00018225
WBCnstr00036006
Regulate_expr_clusterWBPaper00044030:nhr-8(hd117)_downregulated
WBPaper00044030:nhr-8(hd117)_upregulated
WBPaper00062446:nhr-8(hd117)_downregulated
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062446:nhr-8(ok186)_downregulated
WBPaper00062446:nhr-8(ok186)_upregulated
Microarray_results (29)
Expression_cluster (165)
InteractionWBInteraction000006254
WBInteraction000006370
WBInteraction000122604
WBInteraction000122789
WBInteraction000135583
WBInteraction000135584
WBInteraction000143144
WBInteraction000148664
WBInteraction000158437
WBInteraction000158532
WBInteraction000158533
WBInteraction000158534
WBInteraction000158535
WBInteraction000158536
WBInteraction000158537
WBInteraction000158538
WBInteraction000158539
WBInteraction000159346
WBInteraction000161835
WBInteraction000161836
WBInteraction000162429
WBInteraction000162430
WBInteraction000162431
WBInteraction000164437
WBInteraction000169505
WBInteraction000173432
WBInteraction000173568
WBInteraction000240484
WBInteraction000240485
WBInteraction000342561
WBInteraction000505421
WBInteraction000520498
WBInteraction000520501
WBInteraction000520502
WBInteraction000527027
WBInteraction000527028
WBInteraction000527029
WBInteraction000527030
WBInteraction000527031
WBInteraction000527032
WBInteraction000527033
WBInteraction000527034
WBInteraction000527035
WBInteraction000527036
WBInteraction000527037
WBInteraction000527038
WBInteraction000527039
WBInteraction000527040
WBInteraction000527041
WBInteraction000527042
WBInteraction000527043
WBInteraction000527044
WBInteraction000527045
WBInteraction000527046
WBInteraction000527047
WBInteraction000527048
WBInteraction000527049
WBInteraction000529390
WBInteraction000531190
WBInteraction000543106
WBInteraction000543107
WBInteraction000544451
WBInteraction000546929
WBInteraction000546932
WBInteraction000557017
WBInteraction000560755
WBInteraction000564464
WBInteraction000570458
WBProcessWBbiopr:00000001
WBbiopr:00000121
Map_infoMapIVPosition3.41773Error0.007272
PositivePositive_cloneF33D4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Y50A3Person_evidenceWBPerson600
Y53H2Person_evidenceWBPerson600
Y54E12Person_evidenceWBPerson600
Mapping_dataMulti_point4520
Pseudo_map_position
Reference (53)
Remarkcm14e12 unnecessary in sequence list. sdm 11/00
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene