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WormBase Tree Display for Gene: WBGene00003426

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Name Class

WBGene00003426SMapS_parentSequenceF36H12
IdentityVersion1
NameCGC_namemsp-19Person_evidenceWBPerson680
Sequence_nameF36H12.7
Molecular_nameF36H12.7
F36H12.7.1
CE02806
Other_nameCELE_F36H12.7Accession_evidenceNDBBX284604
Public_namemsp-19
DB_infoDatabaseAceViewgene4G25
WormQTLgeneWBGene00003426
WormFluxgeneWBGene00003426
NDBlocus_tagCELE_F36H12.7
PanthergeneCAEEL|WormBase=WBGene00003426|UniProtKB=P53017
familyPTHR22920
NCBIgene177305
RefSeqproteinNM_001380219.1
SwissProtUniProtAccP53017
UniProt_GCRPUniProtAccP53017
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:31WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmsp
AlleleWBVar00276507
WBVar01499365
WBVar00909457
WBVar01499754
WBVar01499395
WBVar01499396
WBVar00424881
WBVar01499242
WBVar01499633
WBVar01500245
Legacy_information[C.elegansII] NMK. Encodes MSP (16kD); msp-113 cluster. [Ward et al. (1988); BA]
RNASeq_FPKM (74)
GO_annotation00047984
00047985
00047986
00047987
00047988
Ortholog (22)
Paralog (50)
Structured_descriptionConcise_descriptionmsp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.Paper_evidenceWBPaper00001023
WBPaper00002143
WBPaper00004280
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated26 Apr 2005 00:00:00
Automated_descriptionPredicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Expressed in gonad; oocyte; and sperm.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF36H12.7
Corresponding_transcriptF36H12.7.1
Other_sequenceGW407950.1
GW409550.1
HC04637
GW411381.1
PTC01347_1
GW407605.1
Associated_featureWBsf228280
Experimental_infoRNAi_result (18)
Expr_patternExpr3417
Expr1150418
Expr2013772
Expr2032008
Drives_constructWBCnstr00036124
Construct_productWBCnstr00036124
AntibodyWBAntibody00000037
WBAntibody00000038
WBAntibody00000854
WBAntibody00000855
WBAntibody00000856
WBAntibody00000857
WBAntibody00000858
Microarray_resultsSMD_F36H12.7
SMD_F36H12.7:2
Aff_F36H12.7
GPL13394_WBGene00003426
GPL13914_F36H12.7
GPL8673_F36H12_7P00044
Expression_clusterWBPaper00029047:atx-3_upregulated
WBPaper00035269:cde-1_regulated
WBPaper00038118:aak-2(gt33)_downregulated
WBPaper00038237:age-1_upregulated_intestine_rescue
WBPaper00038237:age-1_upregulated_neuron_rescue
WBPaper00038237:age-1_upregulated_nontransgenic
WBPaper00038289:oocyte_protein
WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00040560:hpl-2_embryo_downregulated
WBPaper00041071:spe-44_downregulated
WBPaper00041954:ethanol_upregulated
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00043945:MeHg_downregulated
WBPaper00044616:alg-3-4_downregulated_gene
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00044760:germline_specific
WBPaper00045521:Spermatogenic
WBPaper00045729:gld-2(RNAi)_upregulated
WBPaper00046012:tdp-1(ok803)_downregulated
WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
WBPaper00046795:starvation_upregulated
WBPaper00046805:csr-1(RNAi)_upregulated_Set1
WBPaper00046805:csr-1(RNAi)_upregulated_Set2
WBPaper00046805:P-granule-RNAi_upregulated_Set1
WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
WBPaper00048611:MnCl2_downregulated
WBPaper00048988:neuron_expressed
WBPaper00049489:AMsh-glia_enriched
WBPaper00049498:npr-1(ur89)_regulated_2
WBPaper00049736:daf-2(e1370)_downregulated_15deg-then-25deg(12hr)
WBPaper00049905:Age_variant_expression
WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
WBPaper00049920:Glucose-Diet_upregulated_N2
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:HeatShock_upregulated_hsf-1(+)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00049954:BPS_downregulated
WBPaper00050225:flp-6(RNAi)_upregulated
WBPaper00050231:male_enriched
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:seam_expressed
WBPaper00051404:alg-1(gk214)_downregulated
WBPaper00051404:alg-2(ok304)_downregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(icb38)_downregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:alovudine_24h_regulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053318:Aging_downregulated_mRNA_N2
WBPaper00053318:mir-71(n4115)_downregulated_mRNA
WBPaper00053599:female_vs_male_downregulated
WBPaper00053657:JU2519_M.humicola-infection_24hr
WBPaper00053664:ins-11(tm1053)_upregulated
WBPaper00053771:up_at_24h-NaCl
WBPaper00054477:cisplatin_downregulated
WBPaper00054493:hpl-2(tm1489)_upregulated
WBPaper00054872:egl-9(sa307)_downregulated
WBPaper00055049:S.gordonii_downregulated
WBPaper00055103:thoc-5(wy822)_downregulated
WBPaper00055354:Rapamycin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Metformin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00055386:eat-2(ad465)_upregulated
WBPaper00055648:sperm_expressed
WBPaper00055827:pfd-6(gk493446)_downregulated
WBPaper00055971:nhl-2(ok818)_20C_downregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00055981:fog-2(q71)_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056161:male_enriched_siRNA
WBPaper00056167:Cry5B_downregulated
WBPaper00056167:ifo-1(kc2)_downregulated
WBPaper00056290:hsp-6(mg585)_downregulated
WBPaper00056446:hsb-1(cg116)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:flcn-1(ok975)_downregulated
WBPaper00056731:human-amylin_downregulated
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_20C
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057068:numr-1(RNAi)_upregulated
WBPaper00057068:numr-1(RNAi)_upregulated_Cadmium
WBPaper00057288:iff-1(RNAi)_upregulated_protein
WBPaper00057347:nhr-14(tm1473)_upreglated
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00058948:npr-8(ok1439)_downregulated_PA14
WBPaper00058948:PA14_upregulated
WBPaper00059117:B.subtilis_upregulated
WBPaper00059175:hlh-17p-XBP-1_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059334:sacy-1(depletion)_regulated
WBPaper00059421:daf-1(m40)_upregulated
WBPaper00059426:Ag-nanoparticles_upregulated
WBPaper00059426:SiO2-nanoparticles_upregulated
WBPaper00059605:mut-16(pk710)_upregulated
WBPaper00059728:5ug_cholesterol_upregulated
WBPaper00059728:20ug_cholesterol_upregulated
WBPaper00059739:hira-1(gk835598)_downregulated_adult
WBPaper00059739:hira-1(gk835598)_upregulated_L4
WBPaper00059763:neuron_expressed
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
WBPaper00060526:plp-1(ok2155)_upregulated
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060744:Radiation_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060909:atfs-1(cmh15)_upregulated
WBPaper00060921:cat-2(e1112)_downregulated
WBPaper00060921:tbh-1(ok1196)_downregulated
WBPaper00060921:tph-1(mg280)_downregulated
WBPaper00061040:eat-2(ad1116)_downregulated
WBPaper00061045:Y56A3A.22(cck200)_upregulated
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061274:hypergravity_15xg_downregulated
WBPaper00061341:28C_24h_downregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061424:Diet_MYb120_upregulated
WBPaper00061424:Diet_MYb131_upregulated
WBPaper00061466:nath-10(icb102)_upregulated
WBPaper00061478:pie-1(ne4433)_upregulated
WBPaper00061479:hda-1(ne4747)_upregulated
WBPaper00061479:hda-1(ne4748)_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061479:prg-1(tm872)_upregulated
WBPaper00061479:ubc-9(ne4833)_upregulated
WBPaper00061527:msp-36-msp-55
WBPaper00061572:oleic-acid-specific_mating_upregulated
WBPaper00061651:Sperm_enriched
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00061853:osm-3(dh441)_downregulated
WBPaper00061853:osm-3(dh441)_downregulated_tunicamycin
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062446:nhr-8(hd117)_downregulated
WBPaper00062456:doxycycline_downregulated_CB4856_protein
WBPaper00062520:qui-1(db104)_downregulated
WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
WBPaper00062590:Aging_downregulated_neuron
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
WBPaper00064156:lipl-4(overexpress)_upregulated
WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
WBPaper00064473:ets-4(rrr16)_upregulated
WBPaper00064539:nhr-114(gk849)_downregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064721:fasn-1(g14)_upregulated_starved
WBPaper00064727:daf-2(e1370)_upregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
WBPaper00065158:AFD_depleted
WBPaper00065734:unc-25(e156)_downregulated
WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_upregulated_N2
WBPaper00065984:pals-17(syb3980)_upregulated
WBPaper00066038:mip-1(how5)_upregulated
WBPaper00066085:hda-3(ok1991)_upregulated
WBPaper00066093:E.coli-purE_upregulated
WBPaper00066110:Cisplatin_upregulated_diploid
WBPaper00066110:Doxorubicin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066118:cyclobutrifluram_upregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
cgc4386_cluster_1_2
cgc4489_group_11
WBPaper00025099:MA_specific
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00027758:Group_III
WBPaper00031184:acrylamide_upregulated
WBPaper00041174:environmental
WBPaper00041174:environmental_prime
[cgc6390]:Cluster_D
[cgc6390]:spermatogenesis-enriched
SAGE_tagSAGE:gtggatcaactccaagtStrandAntisense
SAGE:tggagttctcgacccaaStrandSense
SAGE:gtggatcaacStrandAntisense
SAGE:tggagttctcStrandSense
Interaction (190)
Map_infoMapIVPosition1.58398Error0.000697
PositivePositive_cloneF36H12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001023
WBPaper00001024
WBPaper00015440
WBPaper00024312
WBPaper00041549
WBPaper00057218
Remarkremoved from gmap IV 1.61 [jah/sdm 5/99
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene