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WormBase Tree Display for Gene: WBGene00003064

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Name Class

WBGene00003064EvidencePaper_evidenceWBPaper00005707
SMapS_parentSequenceR10H10
IdentityVersion2
NameCGC_namenfu-1Person_evidenceWBPerson205
Author_evidenceP. Kropp
Sequence_nameR10H10.1
Molecular_nameR10H10.1
R10H10.1.1
CE53043
Other_nameldp-8
CELE_R10H10.1Accession_evidenceNDBBX284604
Public_namenfu-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:30WBPerson1971EventImportedInitial conversion from geneace
219 Apr 2021 01:27:01WBPerson1983Name_changeCGC_namenfu-1
Other_nameldp-8
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnfu
Allele (21)
Possibly_affected_byWBVar02157210
WBVar02157211
WBVar02157212
WBVar02157213
WBVar02157214
WBVar02157215
WBVar02158607
StrainWBStrain00049819
RNASeq_FPKM (74)
GO_annotation00073274
00073275
00073276
00073277
00073278
00073279
00073280
00110539
00110540
00110541
Contained_in_operonCEOP4376
Ortholog (40)
Structured_descriptionConcise_descriptionlpd-8 encodes a homolog of human and mouse HIRA-interacting protein-5; LPD-8 has C-terminal similarity to a domain of NifU observed in thioredoxin-like proteins and domains (COG0694), and is predicted to be mitochondrial on phylogenetic grounds.Paper_evidenceWBPaper00004133
WBPaper00004424
WBPaper00012874
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable 4 iron, 4 sulfur cluster binding activity and iron ion binding activity. Involved in lipid storage. Predicted to be located in mitochondrion. Used to study multiple mitochondrial dysfunctions syndrome 1. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 1. Is an ortholog of human NFU1 (NFU1 iron-sulfur cluster scaffold).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:0080133Homo sapiensPaper_evidenceWBPaper00061852
Curator_confirmedWBPerson324
Date_last_updated18 Jan 2022 00:00:00
Potential_modelDOID:0080133Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:16287)
Models_disease_assertedWBDOannot00001084
WBDOannot00001085
WBDOannot00001086
WBDOannot00001087
WBDOannot00001088
WBDOannot00001089
Molecular_infoCorresponding_CDSR10H10.1
Corresponding_CDS_historyR10H10.1:wp270
Corresponding_transcriptR10H10.1.1
Other_sequence (43)
Associated_featureWBsf228988
Experimental_infoRNAi_result (13)
Expr_patternExpr1014575
Expr1031442
Expr1155403
Expr2013255
Expr2031486
Drives_constructWBCnstr00036253
Construct_productWBCnstr00036253
WBCnstr00042900
WBCnstr00042901
WBCnstr00042902
Microarray_results (19)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00035073:mitochondria_protein
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00045774:clk-1_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00050234:lin-28(RNAi)_upregulated
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055482:pmt-2(RNAi)_downregulated
WBPaper00055626:pry-1(mu38)_upregulated
WBPaper00055648:germline_expressed
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00057288:Cold_upregulated_transcript
WBPaper00057288:iff-1(RNAi)_upregulated_transcript
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058958:100mGy-irradiation-72h_downregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059328:mrps-5(RNAi)_upregulated_protein
WBPaper00060084:cco-1(RNAi)_upregulated_N2
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00061341:28C_48h_downregulated
WBPaper00062293:isp-1(qm150)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062590:Aging_downregulated_hypodermis
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064716:paraquat_upregulated
WBPaper00065258:anchor-cell_enriched
WBPaper00065841:1_2
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4386_cluster_3_6
cgc4489_group_2
WBPaper00025032:cluster_8
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00032948:StarveUp3
WBPaper00034739:N2moreDR1350
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Atrazine_regulated
WBPaper00036286:Pattern_F
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_aging
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00041370:spg-7(RNAi)_upregulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
WBPaper00048637:lin-35(n745)_starvation_downregulated
WBPaper00048989:N2_rapamycin_downregulated
[cgc5767]:cluster_1
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(41_min)
[cgc5767]:expression_class_MD_pd(53_min)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
[cgc6390]:intrinsic
Interaction (49)
WBProcessWBbiopr:00000121
Map_infoMapIVPosition4.57979Error0.000279
PositivePositive_cloneR10H10Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene