WormBase Tree Display for Gene: WBGene00003011
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WBGene00003011 | SMap | S_parent | Sequence | CHROMOSOME_V | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | lin-25 | Person_evidence | WBPerson261 | |||
Sequence_name | F56H9.5 | ||||||
Molecular_name | F56H9.5 | ||||||
F56H9.5.1 | |||||||
CE05975 | |||||||
Other_name | mdt-24 | Person_evidence | WBPerson3947 | ||||
CELE_F56H9.5 | Accession_evidence | NDB | BX284605 | ||||
Public_name | lin-25 | ||||||
DB_info | Database | AceView | gene | 5N137 | |||
WormQTL | gene | WBGene00003011 | |||||
SignaLink | protein | WBGene00003011 | |||||
WormFlux | gene | WBGene00003011 | |||||
NDB | locus_tag | CELE_F56H9.5 | |||||
NCBI | gene | 179732 | |||||
RefSeq | protein | NM_073761.8 | |||||
SwissProt | UniProtAcc | Q10573 | |||||
TREEFAM | TREEFAM_ID | TF316646 | |||||
UniProt_GCRP | UniProtAcc | Q10573 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | lin | ||||||
Reference_allele | WBVar00144008 | ||||||
Allele (91) | |||||||
Legacy_information | e1446 : adult hermaphrodite vulvaless 11% sterile. ES2. HME1. Males morphologically wildtype ME0. NA2 (n545ts (at 25x resembles e1446 at 15x 8% Vul)). | ||||||
[Tuck SP] lin for lineage abnormal. Hermaphrodites are Egl | |||||||
See also e1446, n545, n1062, n1063 | |||||||
[C.elegansII] e1446 : adult hermaphrodite vulvaless,11% sterile. VPC all 3ary except P6.p. Suppresses lin-1, let-60(gf), not lin-12(gf).ES2. HME1. Males morphologically wildtype ME0. OA9: n545ts (at 25C resembles e1446, at 15C 8% Vul), n1063, ku78, ar90 (probable null, resembles e1446), etc. Cloned: encodes predicted 1139 aa novel protein. [Tuck and Greenwald 1995; GS] | |||||||
Strain | WBStrain00026528 | ||||||
WBStrain00026804 | |||||||
WBStrain00026902 | |||||||
WBStrain00027100 | |||||||
WBStrain00005521 | |||||||
WBStrain00008013 | |||||||
WBStrain00008017 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Ortholog (27) | |||||||
Structured_description | Concise_description | lin-25 encodes a divergent homolog of the TRAP100/Med24 subunit of the Mediator complex; during development, lin-25 functions downstream of let-60 ras to regulate fate specification and differentiation of a number of cell types such as the vulval precursor cells; targets of LIN-25 activity include the lin-39 Hox gene, whose transcriptional upregulation during vulval cell fate specification is dependent upon lin-25; LIN-25 is expressed in vulval precursor cells, hypodermal seam cells, and cells in the somatic gonad; LIN-25 is detected in nuclei, but also seen in the cytoplasm. | Paper_evidence | WBPaper00003330 | |||
WBPaper00004407 | |||||||
WBPaper00027035 | |||||||
WBPaper00035311 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 03 May 2007 00:00:00 | ||||||
Automated_description | Involved in defense response to Gram-positive bacterium and vulval development. Acts upstream of or within with a positive effect on cell fate specification. Located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite distal tip cell; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F56H9.5 | |||||
Corresponding_transcript | F56H9.5.1 | ||||||
Other_sequence | CJC16777 | ||||||
Associated_feature | WBsf647392 | ||||||
WBsf661921 | |||||||
WBsf1001624 | |||||||
WBsf1020604 | |||||||
WBsf232679 | |||||||
WBsf232680 | |||||||
WBsf232681 | |||||||
Experimental_info | RNAi_result | WBRNAi00067753 | Inferred_automatically | RNAi_primary | |||
WBRNAi00095285 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00048794 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00067528 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00015856 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1293 | ||||||
Expr1023216 | |||||||
Expr1031405 | |||||||
Expr1152543 | |||||||
Expr2013169 | |||||||
Expr2031401 | |||||||
Drives_construct | WBCnstr00004617 | ||||||
WBCnstr00004618 | |||||||
WBCnstr00036286 | |||||||
Construct_product | WBCnstr00004617 | ||||||
WBCnstr00004618 | |||||||
WBCnstr00036286 | |||||||
Antibody | WBAntibody00000201 | ||||||
Microarray_results (20) | |||||||
Expression_cluster (113) | |||||||
Interaction (66) | |||||||
Map_info | Map | V | Position | 4.60018 | Error | 0.006913 | |
Well_ordered | |||||||
Positive | Positive_clone | F56H9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
YSL59 | |||||||
Negative | Negative_clone | W05B10 | |||||
Mapping_data | 2_point | 6095 | |||||
6096 | |||||||
6097 | |||||||
6098 | |||||||
Multi_point (25) | |||||||
Pos_neg_data | 1756 | ||||||
6864 | |||||||
7400 | |||||||
Reference (69) | |||||||
Method | Gene |