WormBase Tree Display for Gene: WBGene00002999
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| WBGene00002999 | SMap | S_parent | Sequence | C09H6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lin-10 | Person_evidence | WBPerson261 | |||||
| Sequence_name | C09H6.2 | ||||||||
| Molecular_name | C09H6.2a | ||||||||
| C09H6.2a.1 | |||||||||
| CE15610 | |||||||||
| C09H6.2b | |||||||||
| CE27060 | |||||||||
| C09H6.2c | |||||||||
| CE42752 | |||||||||
| C09H6.2b.1 | |||||||||
| C09H6.2c.1 | |||||||||
| Other_name | CELE_C09H6.2 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | lin-10 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Reference_allele | WBVar00144007 | ||||||||
| Allele (110) | |||||||||
| Possibly_affected_by | WBVar02157231 | ||||||||
| Legacy_information | e1439 : adult hermaphrodite vulvaless (penetrance 95%) HME2; adult male wildtype ME3. Similar phenotype in e1439/Df. NA3 (e1438 n299). | ||||||||
| See also e1438, e1439, n299, n1299, n1329 | |||||||||
| [C.elegansII] e1439 : adult hermaphrodite vulvaless (penetrance 95%) HME2; adult male wildtype ME3. Similar phenotype in e1439/Df. OA>5; e1438, n299, n1299, n1329, n1638amb, etc.C loned: encodes predicted 407aa novel protein;antibody staining indicates ubiquitous,cytoplasmic. [Kim and Horvitz 1990; MT; SD] | |||||||||
| Strain (20) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (45) | |||||||||
| Ortholog (48) | |||||||||
| Structured_description | Concise_description | lin-10 encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi. | Paper_evidence | WBPaper00003214 | |||||
| WBPaper00003566 | |||||||||
| WBPaper00005047 | |||||||||
| WBPaper00005666 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 22 Sep 2011 00:00:00 | ||||||||
| Automated_description | Enables small GTPase binding activity. Involved in several processes, including neuron-neuron synaptic transmission; positive regulation of backward locomotion; and protein localization. Located in several cellular components, including Golgi trans cisterna; somatodendritic compartment; and trans-Golgi network transport vesicle. Expressed in several structures, including ganglia; somatic gonad precursor; somatic nervous system; vulva; and vulval precursor cell. Is an ortholog of human APBA1 (amyloid beta precursor protein binding family A member 1) and APBA2 (amyloid beta precursor protein binding family A member 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C09H6.2a | |||||||
| C09H6.2b | |||||||||
| C09H6.2c | |||||||||
| Corresponding_CDS_history | C09H6.2:wp47 | ||||||||
| Corresponding_transcript | C09H6.2a.1 | ||||||||
| C09H6.2b.1 | |||||||||
| C09H6.2c.1 | |||||||||
| Other_sequence (62) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00091423 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00040271 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113309 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002925 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00070634 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00070635 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00070633 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001261 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113080 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (19) | |||||||||
| Drives_construct | WBCnstr00001376 | ||||||||
| WBCnstr00002227 | |||||||||
| WBCnstr00002228 | |||||||||
| WBCnstr00004259 | |||||||||
| WBCnstr00013409 | |||||||||
| WBCnstr00036296 | |||||||||
| WBCnstr00042475 | |||||||||
| Construct_product | WBCnstr00000853 | ||||||||
| WBCnstr00006573 | |||||||||
| WBCnstr00007502 | |||||||||
| WBCnstr00007503 | |||||||||
| WBCnstr00007925 | |||||||||
| WBCnstr00012383 | |||||||||
| WBCnstr00013263 | |||||||||
| WBCnstr00013409 | |||||||||
| WBCnstr00036296 | |||||||||
| WBCnstr00042475 | |||||||||
| Antibody | WBAntibody00000230 | ||||||||
| WBAntibody00000975 | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (167) | |||||||||
| Interaction (182) | |||||||||
| Map_info (5) | |||||||||
| Reference (184) | |||||||||
| Remark | lin-10 is NOT T01G9.2 [jah 8/99] | ||||||||
| Method | Gene |
