WormBase Tree Display for Gene: WBGene00002998
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| WBGene00002998 | SMap | S_parent | Sequence | ZK637 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lin-9 | Person_evidence | WBPerson261 | |||||
| Sequence_name | ZK637.7 | ||||||||
| Molecular_name | ZK637.7a | ||||||||
| ZK637.7a.1 | |||||||||
| CE28194 | |||||||||
| ZK637.7b | |||||||||
| CE28195 | |||||||||
| ZK637.7b.1 | |||||||||
| Other_name | CELE_ZK637.7 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | lin-9 | ||||||||
| DB_info | Database | AceView | gene | 3J990 | |||||
| WormQTL | gene | WBGene00002998 | |||||||
| WormFlux | gene | WBGene00002998 | |||||||
| NDB | locus_tag | CELE_ZK637.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002998|UniProtKB=P30630 | |||||||
| family | PTHR21689 | ||||||||
| NCBI | gene | 176256 | |||||||
| RefSeq | protein | NM_001027844.5 | |||||||
| NM_001027845.6 | |||||||||
| SwissProt | UniProtAcc | P30630 | |||||||
| TREEFAM | TREEFAM_ID | TF314315 | |||||||
| UniProt_GCRP | UniProtAcc | P30630 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lin | ||||||||
| Allele (58) | |||||||||
| Legacy_information | n112 : adult hermaphrodite wildtype Muv in homozygotes with lin-8 or lin-38. NA3 (n942 n943 (sterile non-Muv alone sterile Muv with lin-8 etc.). | ||||||||
| See also n112, n942, n943 | |||||||||
| [C.elegansII] n112 : adult hermaphrodite wildtype Muv in homozygotes with lin-8 or lin-38. OA2: n942, n943 (both sterile non-Muv alone; sterile Muv with lin-8 etc.). Cloned: encodes predicted 642 aa novel protein, hydrophobic, possible C-term transmembrane domains. [Ferguson and Horvitz 1989; MT] | |||||||||
| Strain (12) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Contained_in_operon | CEOP3878 | ||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | lin-9 encodes two novel proteins that are conserved amongst C. elegans, Drosophila, plants, and vertebrates; lin-9 activity is required redundantly with activity of the synMuv A genes, such as lin-8, for negative regulation of the RTK/Ras-mediated signal transduction pathway that controls vulval development; in addition, lin-9 activity is required non-redundantly for hermaphrodite gonadal sheath cell development (and thus, reproduction), as well as for development of the male reproductive system including the male sensory rays and spicules. | Paper_evidence | WBPaper00000496 | |||||
| WBPaper00004314 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 02 Feb 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA binding activity. Involved in embryo development; male sex differentiation; and regulation of multicellular organismal development. Part of DRM complex. Is an ortholog of human LIN9 (lin-9 DREAM MuvB core complex component). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK637.7a | |||||||
| ZK637.7b | |||||||||
| Corresponding_CDS_history | ZK637.7:wp52 | ||||||||
| Corresponding_transcript | ZK637.7a.1 | ||||||||
| ZK637.7b.1 | |||||||||
| Other_sequence (23) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Expr1024919 | ||||||||
| Expr1031395 | |||||||||
| Expr1163007 | |||||||||
| Expr2013202 | |||||||||
| Expr2031434 | |||||||||
| Drives_construct | WBCnstr00000434 | ||||||||
| WBCnstr00036297 | |||||||||
| Construct_product | WBCnstr00000434 | ||||||||
| WBCnstr00036297 | |||||||||
| Antibody | WBAntibody00001175 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (150) | |||||||||
| Interaction (93) | |||||||||
| Map_info | Map | III | Position | -0.006983 | Error | 0.001785 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | ZK637 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 406 | |||||||
| 407 | |||||||||
| Multi_point | 325 | ||||||||
| 384 | |||||||||
| 385 | |||||||||
| 386 | |||||||||
| 387 | |||||||||
| 758 | |||||||||
| 759 | |||||||||
| 4957 | |||||||||
| 5435 | |||||||||
| Reference (79) | |||||||||
| Method | Gene |
