WormBase Tree Display for Gene: WBGene00002915
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WBGene00002915 | Evidence | CGC_data_submission | ||||
---|---|---|---|---|---|---|
SMap | S_parent | Sequence | H19M22 | |||
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | let | |||||
Allele (416) | ||||||
Possibly_affected_by | WBVar02152894 | |||||
WBVar02152895 | ||||||
WBVar02152896 | ||||||
WBVar02152897 | ||||||
WBVar02152898 | ||||||
WBVar02152899 | ||||||
WBVar02152900 | ||||||
Strain | WBStrain00033530 | |||||
WBStrain00026589 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00022979 | |||||
00022980 | ||||||
00022981 | ||||||
00022982 | ||||||
00022983 | ||||||
00022984 | ||||||
00091539 | ||||||
00100800 | ||||||
00100801 | ||||||
Ortholog (31) | ||||||
Paralog | WBGene00007687 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||
WBGene00011326 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00017013 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00020516 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Concise_description | let-805 encodes myotactin, a novel single-transmembrane protein containing extracellular fibronectin repeats; genetic analyses indicate that LET-805 is essential for proper association between hypodermal fibrous organelles and the contractile apparatus of muscle cells; LET-805 is expressed in hypodermal cells and in the pharynx and localizes to basolateral membranes. | Paper_evidence | WBPaper00003643 | ||
WBPaper00025137 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 09 Jan 2009 00:00:00 | |||||
Automated_description | Predicted to enable cytokine binding activity and cytokine receptor activity. Involved in hemidesmosome assembly. Located in hemidesmosome. Expressed in hypodermal cell; hypodermis; pharynx; touch receptor neurons; and uterine seam cell. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and vesicoureteral reflux. Is an ortholog of human TNXB (tenascin XB). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:9620 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11976) | |
DOID:13359 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11976) | |||
Molecular_info | Corresponding_CDS | H19M22.2a | ||||
H19M22.2b | ||||||
H19M22.2c | ||||||
H19M22.2d | ||||||
Corresponding_transcript | H19M22.2a.1 | |||||
H19M22.2b.1 | ||||||
H19M22.2c.1 | ||||||
H19M22.2d.1 | ||||||
Other_sequence (67) | ||||||
Associated_feature (34) | ||||||
Experimental_info | RNAi_result (16) | |||||
Expr_pattern | Expr1192 | |||||
Expr1193 | ||||||
Expr13531 | ||||||
Expr1028294 | ||||||
Expr1031372 | ||||||
Expr1153159 | ||||||
Expr2013078 | ||||||
Expr2031310 | ||||||
Antibody | WBAntibody00000057 | |||||
Microarray_results (50) | ||||||
Expression_cluster (205) | ||||||
Interaction (19) | ||||||
Map_info (5) | ||||||
Reference (27) | ||||||
Remark | H19M22.2e was disconnected from let-805 [Blasiar D][030411 ck1] | |||||
Method | Gene |