WormBase Tree Display for Gene: WBGene00002267

WBGene00002267 SMap: S_parent: Sequence: C44F1
  Identity: Version: 1
    Name: CGC_name: lec-4
      Sequence_name: C44F1.3
      Molecular_name: C44F1.3
        C44F1.3.1
        CE02163
      Other_name: CELE_C44F1.3 Accession_evidence: NDB BX284603
      Public_name: lec-4
    DB_info: Database: AceView gene 3E862
        WormQTL gene WBGene00002267
        WormFlux gene WBGene00002267
        NDB locus_tag CELE_C44F1.3
        Panther gene CAEEL|WormBase=WBGene00002267|UniProtKB=Q18625
          family PTHR11346
        NCBI gene 175488
        RefSeq protein NM_065362.9
        TrEMBL UniProtAcc Q18625
        UniProt_GCRP UniProtAcc Q18625
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lec
    Allele (34)
    Legacy_information: [Arata Y] No mutants known. Encodes predicted galectin. Predicted gene C44F1.3
    RNASeq_FPKM (74)
    GO_annotation: 00061868
      00061869
      00061870
      00061871
      00061872
      00110339
    Ortholog: WBGene00054801 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00030849 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00151467 Caenorhabditis brenneri From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00092167 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
      WBGene00120300 Caenorhabditis japonica From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00223028 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5720 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g710 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g10970 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g22276 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g16272 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g22453 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g6404 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g7127 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g18079 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g8188 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00013.g942 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-lec-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold552.g3657 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00014.g905 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_10251 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009738 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g12618 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g13067 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30226400 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7315 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00207210 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00218605 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00240064 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00290216 Trichuris muris From_analysis: WormBase-Compara
      WBGene00301846 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0034365 Drosophila melanogaster From_analysis: Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040718-159 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-030131-9543 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-060312-19 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-040724-22 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-070822-22 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-131119-90 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:6570 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            Panther
            SonicParanoid
      HGNC:24842 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            Panther
            SonicParanoid
      MGI:109496 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
      RGD:3005 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoInspector
            Panther
            SonicParanoid
    Paralog (28)
    Structured_description: Concise_description: lec-4 encodes a predicted galectin that exhibits sugar binding properties in vitro. Paper_evidence: WBPaper00004274
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables galactoside binding activity. Located in membrane raft. Is an ortholog of human LGALS9 (galectin 9) and LGALS9B (galectin 9B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C44F1.3
    Corresponding_transcript: C44F1.3.1
    Other_sequence (192)
    Associated_feature: WBsf650931
      WBsf991899
      WBsf991900
      WBsf991901
      WBsf1014631
      WBsf1014632
      WBsf226390
      WBsf226391
      WBsf226392
  Experimental_info: RNAi_result: WBRNAi00011953 Inferred_automatically: RNAi_primary
      WBRNAi00042492 Inferred_automatically: RNAi_primary
      WBRNAi00006002 Inferred_automatically: RNAi_primary
      WBRNAi00092920 Inferred_automatically: RNAi_primary
      WBRNAi00029813 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1025418
      Expr1146479
      Expr2013037
      Expr2031269
    Drives_construct: WBCnstr00036345
    Construct_product: WBCnstr00036345
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:Cluster_5
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037777:lipid_raft_proteins
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_larva_enriched
      WBPaper00037950:excretory-cell_larva_SelectivelyEnriched
      WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038061:aldicarb_downregulated
      WBPaper00038289:oocyte_protein
      WBPaper00044034:LEC-1_associated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046303:P.aeruginosa_upregulated_protein
      WBPaper00046337:monosomal_N2_vs_daf-2_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00050448:KGB-1-induced
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050636:aging_regulated_insoluble_protein
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_nucleus_expressed
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056218:daf-16(mu86)_upregulated_Day3
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056826:SGP_biased
      WBPaper00056900:PID-3_interacting
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059537:ngn-1(ok2200)_upregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:Anterior_arcade_cell
      WBPaper00061340:Arcade_cell_anterior_and_posterior
      WBPaper00061340:CEPso
      WBPaper00061340:M_cell
      WBPaper00061340:Posterior_arcade_cell
      WBPaper00061340:Rectal_gland
      WBPaper00061340:Y
      WBPaper00061340:Z1_Z4
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061527:ttr-18-C54D10.3
      WBPaper00061651:AVA_enriched
      WBPaper00061651:PHso_enriched
      WBPaper00061651:Rectal_gland_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061823:mex-3(spr9)_downregulated
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_protein
      WBPaper00064005:starvation_upregulated_N2_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00065032:PAO1_vs_Delt.Pf4-infection_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:11_2
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066085:hda-3(ok1991)_upregulated
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_2_5
      WBPaper00025032:cluster_61
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00032948:StarveUp2
      WBPaper00035227:heat_shock_regulated
      WBPaper00036286:Pattern_C
      WBPaper00037695:LD_3-day
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:Q50_up
      WBPaper00040963:Q200_up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(66_min)
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:Cluster_A
    Interaction: WBInteraction000538828
      WBInteraction000540312
      WBInteraction000552309
      WBInteraction000552501
      WBInteraction000560845
      WBInteraction000561989
      WBInteraction000564012
      WBInteraction000567096
      WBInteraction000568248
  Map_info: Map: III Position: -4.25302 Error: 0.000245
    Positive: Positive_clone: C44F1 Person_evidence: WBPerson763
          Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004274
    WBPaper00032075
    WBPaper00034766
    WBPaper00037777
    WBPaper00038491
    WBPaper00055090
    WBPaper00061547
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene