WormBase Tree Display for Gene: WBGene00002241
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| WBGene00002241 | SMap | S_parent | Sequence | F10C2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | kup-1 | Person_evidence | WBPerson71 | |||||
| Sequence_name | F10C2.2 | ||||||||
| Molecular_name | F10C2.2 | ||||||||
| F10C2.2.1 | |||||||||
| CE09306 | |||||||||
| Other_name | kup1 | Accession_evidence | EMBL | L12247 | |||||
| CELE_F10C2.2 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | kup-1 | ||||||||
| DB_info | Database | AceView | gene | 5M514 | |||||
| WormQTL | gene | WBGene00002241 | |||||||
| WormFlux | gene | WBGene00002241 | |||||||
| NDB | locus_tag | CELE_F10C2.2 | |||||||
| NCBI | gene | 179651 | |||||||
| RefSeq | protein | NM_001392622.1 | |||||||
| SwissProt | UniProtAcc | P34705 | |||||||
| UniProt_GCRP | UniProtAcc | P34705 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | kup | ||||||||
| Allele (99) | |||||||||
| Legacy_information | [C.elegansII] NMK. Upstream in operon with kin-13. Encodes predicted 385 aa novel protein. Antibody stains nuclei of most cells. [Zorio et al. 1994; CR] | ||||||||
| Strain | WBStrain00035751 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| Contained_in_operon | CEOP5312 | ||||||||
| Ortholog (27) | |||||||||
| Structured_description | Concise_description | kup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00001950 | |||||
| WBPaper00005493 | |||||||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enriched in several structures, including AVK; MSaapaapa; accessory cell; anterior arcade cell; and g2 based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; glp-1; and gld-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by thirteen chemicals including rotenone; mianserin; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F10C2.2 | |||||||
| Corresponding_transcript | F10C2.2.1 | ||||||||
| Other_sequence (42) | |||||||||
| Associated_feature (30) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00044221 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00013038 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085043 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr12857 | ||||||||
| Expr1021564 | |||||||||
| Expr1031316 | |||||||||
| Expr1148182 | |||||||||
| Expr2012983 | |||||||||
| Expr2031215 | |||||||||
| Drives_construct | WBCnstr00022908 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (139) | |||||||||
| Interaction | WBInteraction000227835 | ||||||||
| WBInteraction000396019 | |||||||||
| WBInteraction000435475 | |||||||||
| WBInteraction000574965 | |||||||||
| WBInteraction000576308 | |||||||||
| Map_info | Map | V | Position | 3.60848 | Error | 0.003861 | |||
| Positive | Positive_clone | F10C2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4470 | |||||||
| 4586 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00001723 | ||||||||
| WBPaper00002006 | |||||||||
| WBPaper00005493 | |||||||||
| WBPaper00010944 | |||||||||
| WBPaper00015440 | |||||||||
| WBPaper00022096 | |||||||||
| WBPaper00031335 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
