WormBase Tree Display for Gene: WBGene00002222
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| WBGene00002222 | Evidence | Paper_evidence | WBPaper00003466 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F20C5 | ||||||
| Identity | Version | 3 | |||||||
| Name | CGC_name | klp-11 | Person_evidence | WBPerson589 | |||||
| Sequence_name | F20C5.2 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | krp95 | Accession_evidence | EMBL | AF149288 | |||||
| CELE_F20C5.2 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | klp-11 | ||||||||
| DB_info | Database | AceView | gene | 4J520 | |||||
| WormQTL | gene | WBGene00002222 | |||||||
| WormFlux | gene | WBGene00002222 | |||||||
| NDB | locus_tag | CELE_F20C5.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002222|UniProtKB=Q19633 | |||||||
| family | PTHR24115 | ||||||||
| NCBI | gene | 177685 | |||||||
| RefSeq | protein | NM_001136383.3 | |||||||
| NM_001268401.2 | |||||||||
| NM_001136382.3 | |||||||||
| NM_001383153.2 | |||||||||
| TrEMBL | UniProtAcc | B3GWB6 | |||||||
| B3GWB7 | |||||||||
| Q19633 | |||||||||
| E5QCG4 | |||||||||
| UniProt_GCRP | UniProtAcc | Q19633 | |||||||
| OMIM | gene | 603754 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 04 Aug 2006 11:49:25 | WBPerson2970 | Event | Acquires_merge | WBGene00002237 | ||||
| 3 | 06 Mar 2018 14:37:33 | WBPerson4025 | Event | Split_into | WBGene00303015 | ||||
| Acquires_merge | WBGene00002237 | ||||||||
| Split_into | WBGene00303015 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | klp | ||||||||
| Allele (81) | |||||||||
| Legacy_information | [Siddiqui SS ] Predicted gene F20C5.2. Related to kinesin like protein by sequence similarity. | ||||||||
| Strain | WBStrain00002305 | ||||||||
| WBStrain00036431 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Contained_in_operon | CEOP4609 | ||||||||
| CEOP5618 | |||||||||
| Ortholog (37) | |||||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | klp-11 encodes a kinesin motor protein that functions as a subunit of C. elegans heterotrimeric kinesin-II; in vitro microtubule gliding assays demonstrate that purified kinesin-II and OSM-3, a homomeric kinesin-II motor, cooperatively generate movement similar to that seen along cilia lacking additional regulatory factors; antibodies to KLP-11 detect high intensity staining in the cilia of chemosensory neurons, with fainter staining detected in the dorsal and ventral nerve cords as well as motor commissures. | Paper_evidence | WBPaper00003466 | |||||
| WBPaper00004178 | |||||||||
| WBPaper00027116 | |||||||||
| WBPaper00028530 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 13 Oct 2008 00:00:00 | ||||||||
| Automated_description | Enables microtubule motor activity. Involved in microtubule-based movement. Part of axonemal heterotrimeric kinesin-II complex. Expressed in amphid neurons; dorsal nerve cord; inner labial neurons; phasmid neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in retinitis pigmentosa 89. Is an ortholog of human KIF3B (kinesin family member 3B) and KIF3C (kinesin family member 3C). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112146 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6320) | ||||
| Molecular_info | Corresponding_CDS | F20C5.2a | |||||||
| F20C5.2c | |||||||||
| F20C5.2d | |||||||||
| F20C5.2f | |||||||||
| Corresponding_CDS_history | F20C5.2:wp52 | ||||||||
| F20C5.2b:wp261 | |||||||||
| F20C5.2c:wp221 | |||||||||
| F20C5.2c:wp242 | |||||||||
| F20C5.2d:wp221 | |||||||||
| F20C5.2d:wp242 | |||||||||
| F20C5.2e:wp242 | |||||||||
| F20C5.2f:wp242 | |||||||||
| F20C5.2g:wp264 | |||||||||
| Corresponding_transcript | F20C5.2a.1 | ||||||||
| F20C5.2c.1 | |||||||||
| F20C5.2d.1 | |||||||||
| F20C5.2f.1 | |||||||||
| Other_sequence (22) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00013605 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00045087 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000743 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00111057 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031160 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1483 | ||||||||
| Expr1271 | |||||||||
| Expr16079 | |||||||||
| Expr1015580 | |||||||||
| Expr1031301 | |||||||||
| Expr1149036 | |||||||||
| Expr2012955 | |||||||||
| Expr2031187 | |||||||||
| Drives_construct | WBCnstr00004390 | ||||||||
| WBCnstr00036376 | |||||||||
| Construct_product | WBCnstr00036376 | ||||||||
| Antibody | WBAntibody00000218 | ||||||||
| Microarray_results | SMD_F20C5.2 | ||||||||
| 175639_s_at | |||||||||
| GPL19516_CGZ0017130 | |||||||||
| GPL21109_F20C5.2a | |||||||||
| GPL3518_CE27986 | |||||||||
| GPL8673_F20C5_2aP01861 | |||||||||
| GPL8673_F20C5_2aP02002 | |||||||||
| GPL8673_F20C5_2aP02203 | |||||||||
| Expression_cluster (165) | |||||||||
| Interaction (48) | |||||||||
| Map_info | Map | IV | Position | 3.96111 | Error | 0.00054 | |||
| Positive | Positive_clone | F20C5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4465 | |||||||
| 4592 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (38) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
