WormBase Tree Display for Gene: WBGene00002202
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| WBGene00002202 | Evidence | Paper_evidence | WBPaper00003768 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C03C10 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | kin-19 | |||||||
| Sequence_name | C03C10.1 | ||||||||
| Molecular_name | C03C10.1 | ||||||||
| C03C10.1.1 | |||||||||
| CE00872 | |||||||||
| C03C10.1.2 | |||||||||
| C03C10.1.3 | |||||||||
| Other_name | CELE_C03C10.1 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | kin-19 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | kin | ||||||||
| Allele (37) | |||||||||
| Strain | WBStrain00001347 | ||||||||
| WBStrain00035749 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (37) | |||||||||
| Paralog (93) | |||||||||
| Structured_description | Concise_description | kin-19 encodes a serine/threonine kinase orthologous to Casein Kinase I (CKI); in the early embryo, kin-19 is a component of both the non-canonical Wnt signaling pathway that regulates endoderm formation in the early embryo as well as the Wnt spindle orientation pathway; during larval development, kin-19 functions in a non-canonical Wnt signaling pathway to control asymmetric division and fate specification in epidermal seam cells; kin-19 also functions with, or in parallel to, the heterochronic pathway to regulate loss of self-renewal and terminal differentiation of epidermal seam cells; KIN-19 localizes to centrosomes, the cytoplasm, and the nucleus. | Paper_evidence | WBPaper00003768 | |||||
| WBPaper00005445 | |||||||||
| WBPaper00024624 | |||||||||
| WBPaper00037838 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 10 Jul 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein serine/threonine kinase activity. Involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytoplasm; and nucleus. Expressed in several structures, including BDU; marginal cell; seam cell; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease and inclusion body myositis. Is an ortholog of human CSNK1A1 (casein kinase 1 alpha 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2451) | ||||
| DOID:3429 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2451) | ||||||
| Molecular_info | Corresponding_CDS | C03C10.1 | |||||||
| Corresponding_transcript | C03C10.1.1 | ||||||||
| C03C10.1.2 | |||||||||
| C03C10.1.3 | |||||||||
| Other_sequence (160) | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (76) | ||||||||
| Expr_pattern | Chronogram833 | ||||||||
| Expr5122 | |||||||||
| Expr5123 | |||||||||
| Expr9170 | |||||||||
| Expr11628 | |||||||||
| Expr1012482 | |||||||||
| Expr1031289 | |||||||||
| Expr1143609 | |||||||||
| Expr2012931 | |||||||||
| Expr2031164 | |||||||||
| Drives_construct | WBCnstr00002240 | ||||||||
| WBCnstr00004267 | |||||||||
| WBCnstr00008751 | |||||||||
| WBCnstr00013766 | |||||||||
| WBCnstr00036390 | |||||||||
| Construct_product | WBCnstr00008751 | ||||||||
| WBCnstr00013766 | |||||||||
| WBCnstr00036390 | |||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (126) | |||||||||
| Interaction (283) | |||||||||
| WBProcess | WBbiopr:00000073 | ||||||||
| Map_info | Map | III | Position | -3.84007 | Error | 0.012705 | |||
| Positive | Positive_clone | C03C10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4458 | |||||||
| Pseudo_map_position | |||||||||
| Reference (26) | |||||||||
| Picture | WBPicture0000013084 | ||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
