WormBase Tree Display for Gene: WBGene00002192
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| WBGene00002192 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | kin-4 | |||||||
| Sequence_name | C10C6.1 | ||||||||
| Molecular_name (29) | |||||||||
| Other_name | CELE_C10C6.1 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | kin-4 | ||||||||
| DB_info | Database (14) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:27 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 20 Jan 2010 16:20:47 | WBPerson4025 | Event | Acquires_merge | WBGene00009040 | ||||
| Acquires_merge | WBGene00009040 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | kin | ||||||||
| Allele (245) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes two protein kinase L isoforms, PKL1 (1528 aa, ST kinase, low in embryos, increases 5-fold on hatching) andPKL2 (1377 aa, different C-term, maximal in embryos, absent in L1). [CR] | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (56) | |||||||||
| Paralog (15) | |||||||||
| Structured_description | Automated_description | Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytoplasm. Expressed in head neurons; intestine; and tail neurons. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 108; female breast cancer; and mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations. Is an ortholog of human MAST1 (microtubule associated serine/threonine kinase 1) and MAST3 (microtubule associated serine/threonine kinase 3). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111403 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19034) | ||||
| DOID:0070394 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19036) | ||||||
| DOID:0050671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19034) | ||||||
| Molecular_info | Corresponding_CDS | C10C6.1a | |||||||
| C10C6.1b | |||||||||
| C10C6.1c | |||||||||
| C10C6.1d | |||||||||
| C10C6.1e | |||||||||
| C10C6.1f | |||||||||
| C10C6.1g | |||||||||
| C10C6.1h | |||||||||
| C10C6.1i | |||||||||
| Corresponding_CDS_history | C10C6.1:wp149 | ||||||||
| Corresponding_transcript (11) | |||||||||
| Other_sequence (45) | |||||||||
| Associated_feature (23) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00113413 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00113414 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000907 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040289 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00113415 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00064529 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010589 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002004 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr14620 | ||||||||
| Expr14621 | |||||||||
| Expr14622 | |||||||||
| Expr14623 | |||||||||
| Expr1015031 | |||||||||
| Expr1031285 | |||||||||
| Expr1144362 | |||||||||
| Expr2012943 | |||||||||
| Expr2031175 | |||||||||
| Drives_construct | WBCnstr00036398 | ||||||||
| WBCnstr00041179 | |||||||||
| WBCnstr00041180 | |||||||||
| WBCnstr00041181 | |||||||||
| Construct_product | WBCnstr00036398 | ||||||||
| WBCnstr00041179 | |||||||||
| WBCnstr00041180 | |||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (159) | |||||||||
| Interaction (100) | |||||||||
| Map_info | Map | IV | Position | 4.98015 | Error | 0.00152 | |||
| Positive | Positive_clone | C10C6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| CR#KIN4 | |||||||||
| Mapping_data | Multi_point | 5044 | |||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
