WormBase Tree Display for Gene: WBGene00002153
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| WBGene00002153 | SMap | S_parent | Sequence | C25A1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | iars-2 | Person_evidence | WBPerson36 | |||||
| WBPerson10953 | |||||||||
| Sequence_name | C25A1.7 | ||||||||
| Molecular_name | C25A1.7 | ||||||||
| C25A1.7.1 | |||||||||
| CE35957 | |||||||||
| Other_name | irs-2 | ||||||||
| CELE_C25A1.7 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | iars-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 29 Jan 2010 14:16:16 | WBPerson2970 | Name_change | CGC_name | iars-2 | ||||
| Other_name | irs-2 | ||||||||
| 3 | 06 Mar 2018 14:37:12 | WBPerson4025 | Event | Split_into | WBGene00303030 | ||||
| Split_into | WBGene00303030 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | iars | ||||||||
| Allele (55) | |||||||||
| Strain | WBStrain00047656 | ||||||||
| WBStrain00051913 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Contained_in_operon | CEOP1588 | ||||||||
| CEOP5628 | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00013677 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00002152 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003073 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003074 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00003415 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00006935 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00006936 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013678 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | iars-2 encodes a predicted mitochondrial isoleucyl-tRNA synthetase (IleRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of isoleucine to its cognate tRNA and is thus required for protein biosynthesis; loss of iars-2 activity via RNA-mediated interference (RNAi) in the hypersensitive rrf-3 strain results in thin animals who grow at slower rates than wild type, indicating that IARS-2 plays a role in regulation of postembryonic growth. | Paper_evidence | WBPaper00006395 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 20 Dec 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable isoleucine-tRNA ligase activity. Predicted to be involved in isoleucyl-tRNA aminoacylation and mitochondrial translation. Predicted to be located in mitochondrion. Is an ortholog of human IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C25A1.7 | |||||||
| Corresponding_CDS_history | C25A1.7:wp219 | ||||||||
| C25A1.7a:wp107 | |||||||||
| C25A1.7a:wp113 | |||||||||
| C25A1.7a:wp255 | |||||||||
| C25A1.7a:wp264 | |||||||||
| C25A1.7b:wp113 | |||||||||
| C25A1.7b:wp264 | |||||||||
| Corresponding_transcript | C25A1.7.1 | ||||||||
| Corresponding_transcript_history | C25A1.7c:wp264 | ||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf656849 | ||||||||
| WBsf656850 | |||||||||
| WBsf218403 | |||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Expr1020306 | ||||||||
| Expr1031264 | |||||||||
| Expr1145180 | |||||||||
| Expr2012661 | |||||||||
| Expr2030897 | |||||||||
| Drives_construct | WBCnstr00037961 | ||||||||
| Construct_product | WBCnstr00037961 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (96) | |||||||||
| Interaction (54) | |||||||||
| Map_info | Map | I | Position | 4.71897 | Error | 0.001123 | |||
| Positive | Positive_clone | C25A1 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00035934 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | dl1 : probably mitochondrial | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
