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WormBase Tree Display for Gene: WBGene00002059

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Name Class

WBGene00002059SMapS_parentSequenceF53A2
IdentityVersion1
NameCGC_nameife-1Person_evidenceWBPerson2
Sequence_nameF53A2.6
Molecular_nameF53A2.6a
F53A2.6a.1
CE16098
F53A2.6b
CE31809
F53A2.6b.1
Other_nameCELE_F53A2.6Accession_evidenceNDBBX284603
Public_nameife-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classife
Allele (19)
Possibly_affected_byWBVar02153073
Legacy_information[Aamodt EJ] ife for Initiation Factor E family. No mutants known.
StrainWBStrain00032301
WBStrain00034451
RNASeq_FPKM (74)
GO_annotation (27)
Contained_in_operonCEOP3784
Ortholog (43)
ParalogWBGene00002060Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002062Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002063Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002061Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionThe ife-1 gene encodes one of five C. elegans homologs of the mRNA cap-binding protein eIF4E; it is specifically required for spermatogenesis, and is expressed in P granules.Paper_evidenceWBPaper00004940
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables RNA 7-methylguanosine cap binding activity and RNA trimethylguanosine cap binding activity. Involved in embryo development; oocyte maturation; and spermatid development. Located in P granule. Expressed in germ line; gonad; oocyte; primary spermatocyte; and secondary spermatocyte. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12849Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3287)
Molecular_infoCorresponding_CDSF53A2.6a
F53A2.6b
Corresponding_CDS_historyF53A2.6:wp85
Corresponding_transcriptF53A2.6a.1
F53A2.6b.1
Other_sequenceCRC00051_1
CBC06235_1
Dviv_isotig21667
EX545640.1
ES566685.1
AE03734
Tcol_isotig13752
Tcir_isotig07741
NBC01687_1
CR07097
XIC02809_1
GR13353
EX009137.1
AYC02913_1
Oden_isotig14855
HCC02443_1
CR08355
CRC01016_1
HBC02966_1
CJC00323_1
XI00572
NB07539
ES744473.1
CJC13365_1
ES563886.1
Oden_isotig14854
HG12063
Acan_isotig09762
HC01278
ES566185.1
DIC00974_1
TSC07645_1
EX501720.1
PPC15736_1
CR02374
Dviv_isotig21666
Hbac_isotig01357
ACC19643_1
Name_isotig04640
DI01432
CR08142
CBC01339_1
CR09060
EX012844.1
CR07772
OOC01533_1
Associated_featureWBsf645703
WBsf645704
WBsf659719
WBsf994861
Experimental_infoRNAi_result (17)
Expr_patternExpr1674
Expr2324
Expr14968
Expr1020608
Expr1031212
Expr1151860
Expr2012685
Expr2030921
Construct_productWBCnstr00021260
Regulate_expr_clusterWBPaper00037963:ife-1(ok1978)_downregulated
AntibodyWBAntibody00000170
Microarray_results (24)
Expression_cluster (168)
Interaction (116)
WBProcessWBbiopr:00000069
Map_infoMapIIIPosition21.2112Error9.8e-05
PositivePositive_cloneF53A2Person_evidenceWBPerson2
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (35)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene