WormBase Tree Display for Gene: WBGene00002059
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| WBGene00002059 | SMap | S_parent | Sequence | F53A2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ife-1 | Person_evidence | WBPerson2 | |||||
| Sequence_name | F53A2.6 | ||||||||
| Molecular_name | F53A2.6a | ||||||||
| F53A2.6a.1 | |||||||||
| CE16098 | |||||||||
| F53A2.6b | |||||||||
| CE31809 | |||||||||
| F53A2.6b.1 | |||||||||
| Other_name | CELE_F53A2.6 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | ife-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ife | ||||||||
| Allele (19) | |||||||||
| Possibly_affected_by | WBVar02153073 | ||||||||
| Legacy_information | [Aamodt EJ] ife for Initiation Factor E family. No mutants known. | ||||||||
| Strain | WBStrain00032301 | ||||||||
| WBStrain00034451 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (27) | |||||||||
| Contained_in_operon | CEOP3784 | ||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00002060 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00002062 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00002063 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00002061 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | The ife-1 gene encodes one of five C. elegans homologs of the mRNA cap-binding protein eIF4E; it is specifically required for spermatogenesis, and is expressed in P granules. | Paper_evidence | WBPaper00004940 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables RNA 7-methylguanosine cap binding activity and RNA trimethylguanosine cap binding activity. Involved in embryo development; oocyte maturation; and spermatid development. Located in P granule. Expressed in germ line; gonad; oocyte; primary spermatocyte; and secondary spermatocyte. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human EIF4E (eukaryotic translation initiation factor 4E) and EIF4E1B (eukaryotic translation initiation factor 4E family member 1B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:12849 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3287) | ||||
| Molecular_info | Corresponding_CDS | F53A2.6a | |||||||
| F53A2.6b | |||||||||
| Corresponding_CDS_history | F53A2.6:wp85 | ||||||||
| Corresponding_transcript | F53A2.6a.1 | ||||||||
| F53A2.6b.1 | |||||||||
| Other_sequence (46) | |||||||||
| Associated_feature | WBsf645703 | ||||||||
| WBsf645704 | |||||||||
| WBsf659719 | |||||||||
| WBsf994861 | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Expr1674 | ||||||||
| Expr2324 | |||||||||
| Expr14968 | |||||||||
| Expr1020608 | |||||||||
| Expr1031212 | |||||||||
| Expr1151860 | |||||||||
| Expr2012685 | |||||||||
| Expr2030921 | |||||||||
| Construct_product | WBCnstr00021260 | ||||||||
| Regulate_expr_cluster | WBPaper00037963:ife-1(ok1978)_downregulated | ||||||||
| Antibody | WBAntibody00000170 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (168) | |||||||||
| Interaction (116) | |||||||||
| WBProcess | WBbiopr:00000069 | ||||||||
| Map_info | Map | III | Position | 21.2112 | Error | 9.8e-05 | |||
| Positive | Positive_clone | F53A2 | Person_evidence | WBPerson2 | |||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference (35) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
