WormBase Tree Display for Gene: WBGene00002052
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| WBGene00002052 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | K05B2 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | ifa-4 | Person_evidence | WBPerson105 | |||||
| WBPerson293 | |||||||||
| Sequence_name | K05B2.3 | ||||||||
| Molecular_name | K05B2.3 | ||||||||
| K05B2.3.1 | |||||||||
| CE47884 | |||||||||
| Other_name | Cel IF A4 | Accession_evidence | EMBL | X70833 | |||||
| CelIF a4 | |||||||||
| CELE_K05B2.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | ifa-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ifa | ||||||||
| Allele (68) | |||||||||
| Strain | WBStrain00032180 | ||||||||
| WBStrain00036427 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (30) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | IFA-4 encodes a nonessential intermediate filament protein that is coexpressed with the essential IF protein IFB-1; IFA-4 binds IFB-1 in blot overlay assays; ifa-4 is expressed in larvae in the pharyngeal-intestinal valve, the rectum, some neurons of the tail, the excretory cell, and the intestine of dauer (but not nondauer) larvae; IFA-4 has no function in RNAi assays. | Paper_evidence | WBPaper00001981 | |||||
| WBPaper00004761 | |||||||||
| WBPaper00006137 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in cellular localization; heterochromatin formation; and nucleus organization. Predicted to be located in intermediate filament; nuclear envelope; and nuclear lamina. Expressed in several structures, including egg-laying apparatus; excretory canal; pharyngeal-intestinal valve; rectum; and spermathecal-uterine valve cell. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||
| DOID:0070296 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| DOID:0080299 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6638) | ||||||
| Molecular_info | Corresponding_CDS | K05B2.3 | |||||||
| Corresponding_CDS_history | K05B2.3:wp86 | ||||||||
| K05B2.3:wp223 | |||||||||
| K05B2.3:wp234 | |||||||||
| Corresponding_transcript | K05B2.3.1 | ||||||||
| Other_sequence (43) | |||||||||
| Associated_feature | WBsf653943 | ||||||||
| WBsf670474 | |||||||||
| WBsf718574 | |||||||||
| WBsf1005120 | |||||||||
| WBsf1022875 | |||||||||
| WBsf237332 | |||||||||
| WBsf237333 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00049966 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00106856 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00098343 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007217 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062643 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062644 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016618 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030247 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2764 | ||||||||
| Expr13744 | |||||||||
| Expr14341 | |||||||||
| Expr14342 | |||||||||
| Expr15157 | |||||||||
| Expr1020591 | |||||||||
| Expr1031205 | |||||||||
| Expr1153662 | |||||||||
| Expr2012678 | |||||||||
| Expr2030914 | |||||||||
| Drives_construct | WBCnstr00010939 | ||||||||
| WBCnstr00036492 | |||||||||
| Construct_product | WBCnstr00010939 | ||||||||
| WBCnstr00036492 | |||||||||
| WBCnstr00042017 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (196) | |||||||||
| Interaction (115) | |||||||||
| Map_info | Map | X | Position | -6.21805 | Error | 0.004098 | |||
| Positive | Positive_clone | K05B2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5635 | |||||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Sequence connection from [Chisholm AD] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
