WormBase Tree Display for Gene: WBGene00002048
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| WBGene00002048 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | B0244 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | ida-1 | Person_evidence | WBPerson71 | |||||
| Sequence_name | B0244.2 | ||||||||
| Molecular_name | B0244.2 | ||||||||
| B0244.2.1 | |||||||||
| CE31867 | |||||||||
| Other_name | ia2 | Accession_evidence | EMBL | AF126740 | |||||
| CELE_B0244.2 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | ida-1 | ||||||||
| DB_info | Database | AceView | gene | 3G855 | |||||
| WormQTL | gene | WBGene00002048 | |||||||
| WormFlux | gene | WBGene00002048 | |||||||
| NDB | locus_tag | CELE_B0244.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00002048|UniProtKB=G5EGJ5 | |||||||
| family | PTHR46106 | ||||||||
| NCBI | gene | 175807 | |||||||
| RefSeq | protein | NM_065844.7 | |||||||
| SwissProt | UniProtAcc | G5EGJ5 | |||||||
| TREEFAM | TREEFAM_ID | TF351976 | |||||||
| UniProt_GCRP | UniProtAcc | G5EGJ5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ida | ||||||||
| Allele | WBVar01416026 | ||||||||
| WBVar02147864 | |||||||||
| WBVar01500260 | |||||||||
| WBVar01263879 | |||||||||
| WBVar01263880 | |||||||||
| WBVar01263881 | |||||||||
| WBVar01263882 | |||||||||
| WBVar00318252 | |||||||||
| WBVar00318253 | |||||||||
| WBVar01263884 | |||||||||
| WBVar01263885 | |||||||||
| WBVar01263886 | |||||||||
| WBVar01263888 | |||||||||
| WBVar01263889 | |||||||||
| WBVar01263890 | |||||||||
| WBVar01939025 | |||||||||
| WBVar01263891 | |||||||||
| WBVar01263892 | |||||||||
| WBVar00829515 | |||||||||
| WBVar00829516 | |||||||||
| WBVar00598601 | |||||||||
| WBVar00829517 | |||||||||
| WBVar00829518 | |||||||||
| WBVar00829519 | |||||||||
| WBVar00829520 | |||||||||
| WBVar01827666 | |||||||||
| WBVar00829521 | |||||||||
| WBVar00829522 | |||||||||
| WBVar00829523 | |||||||||
| WBVar00829524 | |||||||||
| WBVar02132068 | |||||||||
| WBVar00829525 | |||||||||
| WBVar00259499 | |||||||||
| WBVar00829526 | |||||||||
| WBVar00829527 | |||||||||
| WBVar00829528 | |||||||||
| WBVar00829529 | |||||||||
| WBVar00829530 | |||||||||
| WBVar00829531 | |||||||||
| WBVar00829532 | |||||||||
| WBVar00829533 | |||||||||
| WBVar00829534 | |||||||||
| WBVar01962814 | |||||||||
| WBVar00829535 | |||||||||
| WBVar00829536 | |||||||||
| WBVar00829537 | |||||||||
| WBVar00321947 | |||||||||
| WBVar00829538 | |||||||||
| WBVar00321948 | |||||||||
| WBVar00829539 | |||||||||
| WBVar00829540 | |||||||||
| WBVar00829541 | |||||||||
| WBVar00829542 | |||||||||
| WBVar00829543 | |||||||||
| WBVar00829544 | |||||||||
| WBVar00829545 | |||||||||
| WBVar01500122 | |||||||||
| WBVar01500123 | |||||||||
| WBVar00249382 | |||||||||
| WBVar00829546 | |||||||||
| WBVar00829547 | |||||||||
| WBVar00829548 | |||||||||
| WBVar00829549 | |||||||||
| WBVar00829550 | |||||||||
| WBVar00829551 | |||||||||
| WBVar00829552 | |||||||||
| WBVar00052602 | |||||||||
| WBVar00249388 | |||||||||
| WBVar00829553 | |||||||||
| WBVar00829554 | |||||||||
| WBVar00316464 | |||||||||
| WBVar00829555 | |||||||||
| WBVar00316465 | |||||||||
| WBVar00316466 | |||||||||
| WBVar00829556 | |||||||||
| WBVar00316467 | |||||||||
| WBVar00829557 | |||||||||
| WBVar00829558 | |||||||||
| WBVar00829559 | |||||||||
| WBVar00829560 | |||||||||
| WBVar01999615 | |||||||||
| WBVar00829561 | |||||||||
| WBVar00829562 | |||||||||
| WBVar00829563 | |||||||||
| WBVar00829564 | |||||||||
| WBVar00829565 | |||||||||
| WBVar01656704 | |||||||||
| WBVar00829566 | |||||||||
| WBVar01656705 | |||||||||
| WBVar00829567 | |||||||||
| WBVar00829568 | |||||||||
| WBVar00829569 | |||||||||
| WBVar00829570 | |||||||||
| WBVar00829571 | |||||||||
| WBVar02053281 | |||||||||
| WBVar00829572 | |||||||||
| WBVar02053282 | |||||||||
| WBVar00829573 | |||||||||
| WBVar02010519 | |||||||||
| WBVar02010520 | |||||||||
| WBVar02111301 | |||||||||
| WBVar01644818 | |||||||||
| WBVar01644819 | |||||||||
| WBVar01644820 | |||||||||
| WBVar01644821 | |||||||||
| WBVar00061657 | |||||||||
| WBVar01644822 | |||||||||
| WBVar01644823 | |||||||||
| WBVar00398581 | |||||||||
| WBVar00061662 | |||||||||
| WBVar00398582 | |||||||||
| WBVar00091703 | |||||||||
| WBVar00398583 | |||||||||
| WBVar00398584 | |||||||||
| WBVar00398585 | |||||||||
| WBVar00398586 | |||||||||
| WBVar00398587 | |||||||||
| WBVar00398588 | |||||||||
| WBVar00398589 | |||||||||
| WBVar00398590 | |||||||||
| WBVar00398591 | |||||||||
| WBVar00398592 | |||||||||
| WBVar00398593 | |||||||||
| WBVar01995266 | |||||||||
| WBVar00398594 | |||||||||
| WBVar01995267 | |||||||||
| WBVar00398595 | |||||||||
| WBVar00398596 | |||||||||
| WBVar01995268 | |||||||||
| WBVar01995269 | |||||||||
| WBVar00398597 | |||||||||
| WBVar01995271 | |||||||||
| WBVar00398598 | |||||||||
| WBVar00398599 | |||||||||
| WBVar01837624 | |||||||||
| WBVar02147973 | |||||||||
| WBVar00398600 | |||||||||
| WBVar00398601 | |||||||||
| WBVar01566441 | |||||||||
| WBVar00398602 | |||||||||
| WBVar00398603 | |||||||||
| WBVar00398604 | |||||||||
| WBVar00398605 | |||||||||
| WBVar00254064 | |||||||||
| WBVar00066115 | |||||||||
| WBVar00320113 | |||||||||
| WBVar00260340 | |||||||||
| WBVar01903776 | |||||||||
| WBVar01628548 | |||||||||
| WBVar00269775 | |||||||||
| WBVar01710122 | |||||||||
| WBVar00269776 | |||||||||
| WBVar01710123 | |||||||||
| WBVar01710124 | |||||||||
| WBVar01445894 | |||||||||
| WBVar01445896 | |||||||||
| WBVar01445898 | |||||||||
| WBVar01479808 | |||||||||
| WBVar01479809 | |||||||||
| WBVar01445900 | |||||||||
| WBVar01445901 | |||||||||
| WBVar00233743 | |||||||||
| WBVar01396841 | |||||||||
| WBVar01722509 | |||||||||
| WBVar01408648 | |||||||||
| WBVar01408649 | |||||||||
| WBVar01408651 | |||||||||
| Strain | WBStrain00003830 | ||||||||
| WBStrain00003831 | |||||||||
| WBStrain00003832 | |||||||||
| WBStrain00035598 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (39) | |||||||||
| Paralog (64) | |||||||||
| Structured_description | Concise_description | ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles. | Paper_evidence | WBPaper00004433 | |||||
| WBPaper00004518 | |||||||||
| WBPaper00019367 | |||||||||
| WBPaper00019564 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable transmembrane receptor protein tyrosine phosphatase activity. Involved in positive regulation of anterior/posterior axon guidance; positive regulation of neurotransmitter secretion; and ventral cord development. Located in dense core granule and synapse. Expressed in several structures, including buccal cavity; neurons; preanal ganglion; somatic nervous system; and uv1. Used to study Parkinson's disease and diabetes mellitus. Human ortholog(s) of this gene implicated in prediabetes syndrome and type 1 diabetes mellitus. Is an ortholog of human PTPRN2 (protein tyrosine phosphatase receptor type N2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:9351 | Homo sapiens | Paper_evidence | WBPaper00046108 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 28 Feb 2017 00:00:00 | ||||||||
| DOID:14330 | Homo sapiens | Paper_evidence | WBPaper00046108 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 04 Feb 2015 00:00:00 | ||||||||
| Potential_model | DOID:9744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9676,HGNC:9677) | |||||
| DOID:11716 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9677) | ||||||
| Models_disease_in_annotation (2) | |||||||||
| Molecular_info | Corresponding_CDS | B0244.2 | |||||||
| Corresponding_CDS_history | B0244.2:wp86 | ||||||||
| B0244.2b:wp18 | |||||||||
| Corresponding_transcript | B0244.2.1 | ||||||||
| Other_sequence (97) | |||||||||
| Associated_feature (18) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00000950 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00038791 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00038790 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028026 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00009628 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005822 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00009627 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (14) | |||||||||
| Drives_construct (12) | |||||||||
| Construct_product | WBCnstr00000646 | ||||||||
| WBCnstr00005801 | |||||||||
| WBCnstr00006969 | |||||||||
| WBCnstr00008654 | |||||||||
| WBCnstr00018579 | |||||||||
| WBCnstr00036495 | |||||||||
| Antibody | WBAntibody00000901 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (299) | |||||||||
| Interaction (63) | |||||||||
| Map_info | Map | III | Position | -1.44641 | Error | 6.5e-05 | |||
| Positive | Positive_clone | B0244 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4431 | |||||||
| Pseudo_map_position | |||||||||
| Reference (32) | |||||||||
| Remark | Sequence connection from [Zahn TA, Macmorris MA] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
