WormBase Tree Display for Gene: WBGene00002029
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| WBGene00002029 | SMap | S_parent | Sequence | C34F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hst-2 | Person_evidence | WBPerson1831 | |||||
| Sequence_name | C34F6.4 | ||||||||
| Molecular_name | C34F6.4 | ||||||||
| C34F6.4.1 | |||||||||
| CE34159 | |||||||||
| Other_name | CELE_C34F6.4 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | hst-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hst | ||||||||
| Allele (39) | |||||||||
| Strain | WBStrain00029327 | ||||||||
| WBStrain00031513 | |||||||||
| WBStrain00031669 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase; by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid; during development, hst-2 activity is required for normal body size, cell migration, and nervous system development; an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood; expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad. | Paper_evidence | WBPaper00006471 | |||||
| WBPaper00024916 | |||||||||
| WBPaper00029002 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 26 Oct 2007 00:00:00 | ||||||||
| Automated_description | Enables heparan sulfate 2-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification; regulation of growth; and regulation of locomotion. Predicted to be located in Golgi apparatus. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; hermaphrodite distal tip cell; and somatic nervous system. Is an ortholog of human HS2ST1 (heparan sulfate 2-O-sulfotransferase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C34F6.4 | |||||||
| Corresponding_CDS_history | C34F6.4:wp102 | ||||||||
| Corresponding_transcript | C34F6.4.1 | ||||||||
| Other_sequence (24) | |||||||||
| Associated_feature | WBsf654394 | ||||||||
| WBsf671014 | |||||||||
| WBsf237940 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr2902 | ||||||||
| Expr3186 | |||||||||
| Expr12885 | |||||||||
| Expr1015936 | |||||||||
| Expr1031184 | |||||||||
| Expr1145929 | |||||||||
| Expr2012634 | |||||||||
| Expr2030870 | |||||||||
| Drives_construct | WBCnstr00011015 | ||||||||
| WBCnstr00011206 | |||||||||
| WBCnstr00036510 | |||||||||
| Construct_product | WBCnstr00005698 | ||||||||
| WBCnstr00005704 | |||||||||
| WBCnstr00005705 | |||||||||
| WBCnstr00005706 | |||||||||
| WBCnstr00036510 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (117) | |||||||||
| Interaction | WBInteraction000028410 | ||||||||
| WBInteraction000524035 | |||||||||
| Anatomy_function | WBbtf0284 | ||||||||
| Map_info | Map | X | Position | 2.86212 | Error | 0.000352 | |||
| Positive | Positive_clone | C34F6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4384 | |||||||
| 4421 | |||||||||
| 4945 | |||||||||
| 5511 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (28) | |||||||||
| Remark | Sequence connection from [Turnbull J, Kinnunen T]. krb 13/11/01 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
