WormBase Tree Display for Gene: WBGene00002029
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WBGene00002029 | SMap | S_parent | Sequence | C34F6 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | hst | ||||||
Allele (39) | |||||||
Strain | WBStrain00029327 | ||||||
WBStrain00031513 | |||||||
WBStrain00031669 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (21) | |||||||
Ortholog (35) | |||||||
Structured_description | Concise_description | hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase; by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid; during development, hst-2 activity is required for normal body size, cell migration, and nervous system development; an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood; expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad. | Paper_evidence | WBPaper00006471 | |||
WBPaper00024916 | |||||||
WBPaper00029002 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 26 Oct 2007 00:00:00 | ||||||
Automated_description | Enables heparan sulfate 2-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification; regulation of growth; and regulation of locomotion. Predicted to be located in Golgi apparatus. Expressed in several structures, including P6.paa; P6.pap; P6.ppa; hermaphrodite distal tip cell; and somatic nervous system. Is an ortholog of human HS2ST1 (heparan sulfate 2-O-sulfotransferase 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C34F6.4 | |||||
Corresponding_CDS_history | C34F6.4:wp102 | ||||||
Corresponding_transcript | C34F6.4.1 | ||||||
Other_sequence (24) | |||||||
Associated_feature | WBsf654394 | ||||||
WBsf671014 | |||||||
WBsf237940 | |||||||
Experimental_info | RNAi_result (12) | ||||||
Expr_pattern | Expr2902 | ||||||
Expr3186 | |||||||
Expr12885 | |||||||
Expr1015936 | |||||||
Expr1031184 | |||||||
Expr1145929 | |||||||
Expr2012634 | |||||||
Expr2030870 | |||||||
Drives_construct | WBCnstr00011015 | ||||||
WBCnstr00011206 | |||||||
WBCnstr00036510 | |||||||
Construct_product | WBCnstr00005698 | ||||||
WBCnstr00005704 | |||||||
WBCnstr00005705 | |||||||
WBCnstr00005706 | |||||||
WBCnstr00036510 | |||||||
Microarray_results (19) | |||||||
Expression_cluster (117) | |||||||
Interaction | WBInteraction000028410 | ||||||
WBInteraction000524035 | |||||||
Anatomy_function | WBbtf0284 | ||||||
Map_info | Map | X | Position | 2.86212 | Error | 0.000352 | |
Positive | Positive_clone | C34F6 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4384 | |||||
4421 | |||||||
4945 | |||||||
5511 | |||||||
Pseudo_map_position | |||||||
Reference (28) | |||||||
Remark | Sequence connection from [Turnbull J, Kinnunen T]. krb 13/11/01 | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |