WormBase Tree Display for Gene: WBGene00001959
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| WBGene00001959 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C43H6 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | hlh-15 | Person_evidence | WBPerson346 | |||||
| Sequence_name | C43H6.8 | ||||||||
| Molecular_name | C43H6.8 | ||||||||
| C43H6.8.1 | |||||||||
| CE06959 | |||||||||
| Other_name | CELE_C43H6.8 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | hlh-15 | ||||||||
| DB_info | Database | AceView | gene | XD32 | |||||
| WormQTL | gene | WBGene00001959 | |||||||
| WormFlux | gene | WBGene00001959 | |||||||
| NDB | locus_tag | CELE_C43H6.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001959|UniProtKB=Q18590 | |||||||
| family | PTHR13864 | ||||||||
| NCBI | gene | 183427 | |||||||
| RefSeq | protein | NM_076039.2 | |||||||
| SwissProt | UniProtAcc | Q18590 | |||||||
| UniProt_GCRP | UniProtAcc | Q18590 | |||||||
| OMIM | gene | 162361 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hlh | ||||||||
| Allele (11) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOPX032 | ||||||||
| Ortholog (28) | |||||||||
| Structured_description | Concise_description | hlh-15 encodes one of 42 C. elegans basic helix-loop-helix transcription factors; HLH-15 physically interacts with HLH-2, the C. elegans E/Daughterless homolog; an hlh-15::gfp promoter fusion is expressed in head and tail neurons. | Paper_evidence | WBPaper00034761 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 25 Aug 2011 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in positive regulation of DNA-templated transcription. Acts upstream of or within determination of adult lifespan. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism. Is an ortholog of human NHLH2 (nescient helix-loop-helix 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0090070 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7818) | ||||
| Molecular_info | Corresponding_CDS | C43H6.8 | |||||||
| Corresponding_transcript | C43H6.8.1 | ||||||||
| Other_sequence | Tcol_isotig24512 | ||||||||
| JI176672.1 | |||||||||
| Associated_feature | WBsf653742 | ||||||||
| WBsf653743 | |||||||||
| WBsf978325 | |||||||||
| WBsf1004322 | |||||||||
| Transcription_factor | WBTranscriptionFactor000070 | ||||||||
| WBTranscriptionFactor000079 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00042407 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00029777 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011901 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023086 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115663 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1023339 | ||||||||
| Expr1146396 | |||||||||
| Expr2012495 | |||||||||
| Expr2030734 | |||||||||
| Drives_construct | WBCnstr00036559 | ||||||||
| Construct_product | WBCnstr00016892 | ||||||||
| WBCnstr00021793 | |||||||||
| WBCnstr00036559 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (86) | |||||||||
| Interaction | WBInteraction000264801 | ||||||||
| WBInteraction000299090 | |||||||||
| WBInteraction000435383 | |||||||||
| WBInteraction000440447 | |||||||||
| WBInteraction000505563 | |||||||||
| WBInteraction000523899 | |||||||||
| Map_info | Map | X | Position | -15.5661 | Error | 0.010281 | |||
| Positive | Positive_clone | C43H6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5080 | |||||||
| 4339 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027309 | ||||||||
| WBPaper00028261 | |||||||||
| WBPaper00030863 | |||||||||
| WBPaper00034761 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00048923 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059477 | |||||||||
| WBPaper00061738 | |||||||||
| WBPaper00063184 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
