WormBase Tree Display for Gene: WBGene00001898
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| WBGene00001898 | SMap | S_parent | Sequence | M163 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | his-24 | Person_evidence | WBPerson160 | |||||
| Sequence_name | M163.3 | ||||||||
| Molecular_name | M163.3 | ||||||||
| M163.3.1 | |||||||||
| CE12450 | |||||||||
| Other_name | HH1 | ||||||||
| H1.1 | Paper_evidence | WBPaper00004630 | |||||||
| Histone H1.1 | Paper_evidence | WBPaper00053345 | |||||||
| CELE_M163.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | his-24 | ||||||||
| DB_info | Database | AceView | gene | XP109 | |||||
| WormQTL | gene | WBGene00001898 | |||||||
| WormFlux | gene | WBGene00001898 | |||||||
| NDB | locus_tag | CELE_M163.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001898|UniProtKB=P10771 | |||||||
| family | PTHR11467 | ||||||||
| NCBI | gene | 181545 | |||||||
| RefSeq | protein | NM_078009.7 | |||||||
| SwissProt | UniProtAcc | P10771 | |||||||
| UniProt_GCRP | UniProtAcc | P10771 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 12 Nov 2010 10:24:40 | WBPerson2970 | Name_change | Other_name | H1.1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | his | ||||||||
| Allele (33) | |||||||||
| Legacy_information | [C.elegansII] NMK. Histone type H1. Contains intron, encodes polyadenylated RNA. [Sanicola et al. 1990] | ||||||||
| Strain | WBStrain00031772 | ||||||||
| WBStrain00034782 | |||||||||
| WBStrain00034807 | |||||||||
| WBStrain00006458 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00039072 | ||||||||
| 00039073 | |||||||||
| 00039074 | |||||||||
| 00039075 | |||||||||
| 00039076 | |||||||||
| 00039077 | |||||||||
| 00039078 | |||||||||
| 00039079 | |||||||||
| 00039080 | |||||||||
| 00039081 | |||||||||
| 00039082 | |||||||||
| 00039083 | |||||||||
| 00039084 | |||||||||
| 00039085 | |||||||||
| 00039086 | |||||||||
| 00039087 | |||||||||
| 00039088 | |||||||||
| 00039089 | |||||||||
| 00039090 | |||||||||
| 00039091 | |||||||||
| 00039092 | |||||||||
| 00039093 | |||||||||
| 00039094 | |||||||||
| 00039095 | |||||||||
| 00039096 | |||||||||
| 00039097 | |||||||||
| 00109613 | |||||||||
| 00109614 | |||||||||
| 00109615 | |||||||||
| 00109616 | |||||||||
| Ortholog (80) | |||||||||
| Paralog | WBGene00001852 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001853 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001854 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001855 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001856 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001857 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | his-24 encodes one of eight C. elegans H1 linker histones; HIS-24, along with the histone deacetylase SIR-2.1 and the Enhancer of zeste E(Z) ortholog MES-2, plays a key role in heterochromatin regulation and thus, in regulation of fertility and embryonic development; specifically, HIS-24 and SIR-2.1 are essential for maintenance of the histone H3K27me3 mark at subtelomeric regions in the C. elegans germ line; HIS-24 interacts specifically with the H3 K27 region, either when unmodified or when in the trimethylated (me3) state; HIS-24 is ubiquitously expressed and localizes to nuclei; in addition, in germ cells, the majority of HIS-24 localizes to the cytoplasm, in a manner dependent upon SIR-2.1 and MES proteins. | Paper_evidence | WBPaper00004630 | |||||
| WBPaper00028983 | |||||||||
| WBPaper00033091 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 17 Nov 2010 00:00:00 | ||||||||
| Automated_description | Enables H3K27me3 modified histone binding activity. Involved in defense response to Gram-positive bacterium and negative regulation of gene expression. Located in chromosome, telomeric region; cytoplasm; and nucleus. Expressed in several structures, including germ line and gonad. Is an ortholog of human H1-0 (H1.0 linker histone) and H1-8 (H1.8 linker histone). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | M163.3 | |||||||
| Corresponding_transcript | M163.3.1 | ||||||||
| Other_sequence (76) | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00090698 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00017226 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089638 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027719 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089608 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00050989 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076026 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076031 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00064599 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076030 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (15) | |||||||||
| Drives_construct | WBCnstr00000408 | ||||||||
| WBCnstr00000430 | |||||||||
| WBCnstr00002522 | |||||||||
| WBCnstr00007280 | |||||||||
| WBCnstr00009451 | |||||||||
| WBCnstr00013533 | |||||||||
| WBCnstr00015453 | |||||||||
| WBCnstr00015912 | |||||||||
| WBCnstr00036616 | |||||||||
| Construct_product (293) | |||||||||
| Regulate_expr_cluster | WBPaper00041609:hpl-1_hpl-2_downregulated | ||||||||
| WBPaper00041609:hpl-1_hpl-2_upregulated | |||||||||
| Antibody (3) | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (392) | |||||||||
| Interaction (157) | |||||||||
| WBProcess | WBbiopr:00000008 | ||||||||
| WBbiopr:00000039 | |||||||||
| Map_info | Map | X | Position | 16.7093 | Error | 0.005353 | |||
| Positive | Positive_clone | LCEH1A | |||||||
| M163 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Pseudo_map_position | |||||||||
| Reference (29) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
