WormBase Tree Display for Gene: WBGene00001843
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| WBGene00001843 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hgo-1 | |||||||
| Sequence_name | W06D4.1 | ||||||||
| Molecular_name | W06D4.1 | ||||||||
| W06D4.1.1 | |||||||||
| CE29602 | |||||||||
| Other_name | HGO | Accession_evidence | EMBL | AF136150 | |||||
| U95181 | |||||||||
| CELE_W06D4.1 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | hgo-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hgo | ||||||||
| Allele (73) | |||||||||
| Strain | WBStrain00000173 | ||||||||
| WBStrain00003060 | |||||||||
| WBStrain00002597 | |||||||||
| Component_of_genotype | WBGenotype00000124 | ||||||||
| WBGenotype00000126 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP1524 | ||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | hgo-1 encodes a putative homogentisate 1,2-dioxygenase, orthologous to human HGD (OMIM:607474, mutated in alkaptonuria), that is required for normal resistance to hypertonic stress; HGO-1 is expressed in larval and adult hypodermis and intestine, and in larval pharynx; HGO-1 is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals. | Paper_evidence | WBPaper00006525 | |||||
| WBPaper00024542 | |||||||||
| WBPaper00031006 | |||||||||
| WBPaper00031468 | |||||||||
| Curator_confirmed | WBPerson1823 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 02 Mar 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable homogentisate 1,2-dioxygenase activity. Predicted to be involved in L-phenylalanine catabolic process. Located in striated muscle dense body. Expressed in body wall musculature and vulval muscle. Human ortholog(s) of this gene implicated in alkaptonuria. Is an ortholog of human HGD (homogentisate 1,2-dioxygenase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9270 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4892) | ||||
| Molecular_info | Corresponding_CDS | W06D4.1 | |||||||
| Corresponding_CDS_history | W06D4.1:wp67 | ||||||||
| Corresponding_transcript | W06D4.1.1 | ||||||||
| Other_sequence (144) | |||||||||
| Associated_feature | WBsf649438 | ||||||||
| WBsf664656 | |||||||||
| WBsf664657 | |||||||||
| WBsf664658 | |||||||||
| WBsf664659 | |||||||||
| WBsf984560 | |||||||||
| WBsf984561 | |||||||||
| WBsf1010302 | |||||||||
| WBsf220025 | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00003156 | ||||||||
| WBCnstr00004557 | |||||||||
| Construct_product | WBCnstr00013963 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (201) | |||||||||
| Interaction (30) | |||||||||
| Map_info | Map | I | Position | 3.44114 | Error | 0.003712 | |||
| Positive | Positive_clone | W06D4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00024542 | ||||||||
| WBPaper00031468 | |||||||||
| WBPaper00034662 | |||||||||
| WBPaper00036083 | |||||||||
| WBPaper00038444 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059605 | |||||||||
| WBPaper00065140 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
