WormBase Tree Display for Gene: WBGene00001787

WBGene00001787 Evidence: Person_evidence: WBPerson1846
  SMap: S_parent: Sequence: Y53F4B
  Identity: Version: 1
    Name: CGC_name: gst-39
      Sequence_name: Y53F4B.33
      Molecular_name: Y53F4B.33
        Y53F4B.33.1
        CE22420
      Other_name: CELE_Y53F4B.33 Accession_evidence: NDB BX284602
      Public_name: gst-39
    DB_info: Database: AceView gene 2P458
        WormQTL gene WBGene00001787
        WormFlux gene WBGene00001787
        NDB locus_tag CELE_Y53F4B.33
        Panther gene CAEEL|WormBase=WBGene00001787|UniProtKB=Q9NAB0
          family PTHR11571
        NCBI gene 190226
        RefSeq protein NM_064718.5
        TREEFAM TREEFAM_ID TF353041
        TrEMBL UniProtAcc Q9NAB0
        UniProt_GCRP UniProtAcc Q9NAB0
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gst
    Allele (12)
    RNASeq_FPKM (74)
    GO_annotation: 00095918
      00095919
    Ortholog (46)
    Paralog (45)
    Structured_description: Automated_description: Enriched in g1; head mesodermal cell; intestine; muscle cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by twenty-three chemicals including glutathione; methylmercuric chloride; and rotenone based on proteomic; microarray; and RNA-seq studies. Human HPGDS enables metal ion binding activity; prostaglandin-D synthase activity; and protein homodimerization activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, N-terminal; Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal; and Thioredoxin-like superfamily. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y53F4B.33
    Corresponding_transcript: Y53F4B.33.1
    Other_sequence (27)
    Associated_feature: WBsf716535
      WBsf990918
      WBsf1013959
      WBsf224322
  Experimental_info: RNAi_result: WBRNAi00057289 Inferred_automatically: RNAi_primary
      WBRNAi00020946 Inferred_automatically: RNAi_primary
      WBRNAi00115485 Inferred_automatically: RNAi_primary
      WBRNAi00115548 Inferred_automatically: RNAi_primary
      WBRNAi00037427 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027417
      Expr1160726
      Expr2012322
      Expr2030558
    Drives_construct: WBCnstr00036685
    Construct_product: WBCnstr00036685
    Microarray_results (17)
    Expression_cluster: WBPaper00005013:glutathione-binding_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00041075:hcf-1(-)_skn-1(+)_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smg-2(RNAi)_downregulated
      WBPaper00044246:pgrn-1_ced-3_ced-1_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:wdr-5(ok1417)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049217:TCER-1_upregulated
      WBPaper00049266:NaAsO2-Stress_regulated_N2
      WBPaper00049266:NaAsO2-Stress_regulated_trx-1(ok1449)
      WBPaper00049325:CB4856_vs_N2_DEG
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049732:blmp-1(tm548)_vs_N2_downregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049954:BPA_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050332:juglone_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:intestine_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051461:pig-1(gm344)_downregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053664:ins-11(tm1053)_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054191:H3.3(null)_L1_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055226:ADR-2_target_adr-1(tm668)
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056586:mpk-2(ok219)_upregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:skn-1(lax188)_upregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059231:alh-6(lax105)_D3Adult_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060764:swsn-1(os22ts)_upregulated
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061045:Y56A3A.22(cck200)_upregulated
      WBPaper00061340:ADF
      WBPaper00061340:ADL
      WBPaper00061340:ASG
      WBPaper00061340:ASH
      WBPaper00061340:ASJ
      WBPaper00061340:AWA
      WBPaper00061340:g1A
      WBPaper00061340:g1A_g1P
      WBPaper00061340:g1P
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:sdz-8-gst-31
      WBPaper00061651:ASG_enriched
      WBPaper00061651:AVG_enriched
      WBPaper00061651:CEP_enriched
      WBPaper00061651:PDE_enriched
      WBPaper00061902:camt-1(ok515)_regulated_AFD
      WBPaper00062056:lin-36(we31)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065841:41_1
      WBPaper00065841:41_2
      WBPaper00065841:131_0
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_13
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00029437:dcr-1_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_depleted
      WBPaper00031832:slr-2_regulated
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_G
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037695:WC_5-day
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:TA300_up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc6390]:male_sex-enriched
    Interaction (23)
  Map_info: Map: II Position: 24.3474 Error: 0.007795
    Positive: Positive_clone: Y53F4B Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031973
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene