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WormBase Tree Display for Gene: WBGene00001758

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Name Class

WBGene00001758EvidencePerson_evidenceWBPerson1846
SMapS_parentSequenceY45G12C
IdentityVersion1
NameCGC_namegst-10
Sequence_nameY45G12C.2
Molecular_nameY45G12C.2a
Y45G12C.2a.1
CE21937
Y45G12C.2b
CE51120
Y45G12C.2b.1
Other_nameCELE_Y45G12C.2Accession_evidenceNDBBX284605
Public_namegst-10
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgst
Allele (33)
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (66)
Paralog (45)
Structured_descriptionConcise_descriptiongst-10 encodes a glutathione S-transferase with similarity to the pi class of human glutathione S-transferases; GST-10 catalyzes the conjugation of glutathione to 4-hydroxynonenal in vitro.Paper_evidenceWBPaper00004663
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated11 Jan 2012 00:00:00
Automated_descriptionEnables glutathione transferase activity. Involved in several processes, including determination of adult lifespan; heat acclimation; and response to UV-C. Predicted to be located in cytosol. Expressed in head and tail. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00035962
Curator_confirmedWBPerson38202
Date_last_updated29 Jun 2018 00:00:00
Potential_model (139)
Models_disease_in_annotationWBDOannot00000566
Molecular_infoCorresponding_CDSY45G12C.2a
Y45G12C.2b
Corresponding_transcriptY45G12C.2a.1
Y45G12C.2b.1
Other_sequence (11)
Associated_featureWBsf231517
WBsf231518
Experimental_infoRNAi_result (21)
Expr_patternChronogram415
Expr3779
Expr6981
Expr1017258
Expr1031047
Expr1160093
Expr2012293
Expr2030529
Drives_constructWBCnstr00002820
WBCnstr00011654
WBCnstr00036711
Construct_productWBCnstr00011654
WBCnstr00036711
AntibodyWBAntibody00000875
Microarray_results (19)
Expression_cluster (346)
Interaction (46)
Map_infoMapVPosition-14.8306Error0.069584
PositivePositive_cloneY45G12CInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4922
5418
Pseudo_map_position
Reference (26)
RemarkSequence connection from [Engle MR, Zimniak P]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene