WormBase Tree Display for Gene: WBGene00001758
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WBGene00001758 | Evidence | Person_evidence | WBPerson1846 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | Y45G12C | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | gst-10 | |||||||
Sequence_name | Y45G12C.2 | ||||||||
Molecular_name | Y45G12C.2a | ||||||||
Y45G12C.2a.1 | |||||||||
CE21937 | |||||||||
Y45G12C.2b | |||||||||
CE51120 | |||||||||
Y45G12C.2b.1 | |||||||||
Other_name | CELE_Y45G12C.2 | Accession_evidence | NDB | BX284605 | |||||
Public_name | gst-10 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | gst | ||||||||
Allele (33) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (66) | |||||||||
Paralog (45) | |||||||||
Structured_description | Concise_description | gst-10 encodes a glutathione S-transferase with similarity to the pi class of human glutathione S-transferases; GST-10 catalyzes the conjugation of glutathione to 4-hydroxynonenal in vitro. | Paper_evidence | WBPaper00004663 | |||||
Curator_confirmed | WBPerson48 | ||||||||
WBPerson1843 | |||||||||
Date_last_updated | 11 Jan 2012 00:00:00 | ||||||||
Automated_description | Enables glutathione transferase activity. Involved in several processes, including determination of adult lifespan; heat acclimation; and response to UV-C. Predicted to be located in cytosol. Expressed in head and tail. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; autoimmune disease (multiple); carcinoma (multiple); and hematologic cancer (multiple). Is an ortholog of human GSTP1 (glutathione S-transferase pi 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Experimental_model | DOID:9970 | Homo sapiens | Paper_evidence | WBPaper00035962 | ||||
Curator_confirmed | WBPerson38202 | ||||||||
Date_last_updated | 29 Jun 2018 00:00:00 | ||||||||
Potential_model (139) | |||||||||
Models_disease_in_annotation | WBDOannot00000566 | ||||||||
Molecular_info | Corresponding_CDS | Y45G12C.2a | |||||||
Y45G12C.2b | |||||||||
Corresponding_transcript | Y45G12C.2a.1 | ||||||||
Y45G12C.2b.1 | |||||||||
Other_sequence (11) | |||||||||
Associated_feature | WBsf231517 | ||||||||
WBsf231518 | |||||||||
Experimental_info | RNAi_result (21) | ||||||||
Expr_pattern | Chronogram415 | ||||||||
Expr3779 | |||||||||
Expr6981 | |||||||||
Expr1017258 | |||||||||
Expr1031047 | |||||||||
Expr1160093 | |||||||||
Expr2012293 | |||||||||
Expr2030529 | |||||||||
Drives_construct | WBCnstr00002820 | ||||||||
WBCnstr00011654 | |||||||||
WBCnstr00036711 | |||||||||
Construct_product | WBCnstr00011654 | ||||||||
WBCnstr00036711 | |||||||||
Antibody | WBAntibody00000875 | ||||||||
Microarray_results (19) | |||||||||
Expression_cluster (346) | |||||||||
Interaction (46) | |||||||||
Map_info | Map | V | Position | -14.8306 | Error | 0.069584 | |||
Positive | Positive_clone | Y45G12C | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4922 | |||||||
5418 | |||||||||
Pseudo_map_position | |||||||||
Reference (26) | |||||||||
Remark | Sequence connection from [Engle MR, Zimniak P] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |