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WormBase Tree Display for Gene: WBGene00001744

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Name Class

WBGene00001744SMapS_parentSequenceT10F2
IdentityVersion2
NameCGC_namegars-1Person_evidenceWBPerson36
WBPerson10953
Sequence_nameT10F2.1
Molecular_nameT10F2.1a
T10F2.1a.1
CE29472
T10F2.1b
CE32719
T10F2.1b.1
Other_namegrs-1
CELE_T10F2.1Accession_evidenceNDBBX284603
Public_namegars-1
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
229 Jan 2010 14:16:16WBPerson2970Name_changeCGC_namegars-1
Other_namegrs-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgars
Allele (35)
RNASeq_FPKM (74)
GO_annotation (29)
Contained_in_operonCEOP3260
Ortholog (47)
Structured_descriptionConcise_descriptiongrs-1 encodes a member of the glycyl-tRNA synthetase family that affects embryonic viability and spindle maintenance during anaphase.Paper_evidenceWBPaper00004403
WBPaper00004651
WBPaper00005654
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable glycine-tRNA ligase activity and protein dimerization activity. Predicted to be involved in diadenosine tetraphosphate biosynthetic process and mitochondrial glycyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Is an ortholog of human GARS1 (glycyl-tRNA synthetase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111204Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4162)
DOID:0110164Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4162)
Molecular_infoCorresponding_CDST10F2.1a
T10F2.1b
Corresponding_transcriptT10F2.1a.1
T10F2.1b.1
Other_sequence (114)
Associated_featureWBsf666457
WBsf666892
WBsf666893
WBsf666894
WBsf666895
WBsf981468
WBsf992318
WBsf226642
Experimental_infoRNAi_result (21)
Expr_patternExpr1013407
Expr1031037
Expr1156667
Expr2011947
Expr2030184
Drives_constructWBCnstr00037966
Construct_productWBCnstr00037966
Microarray_results (26)
Expression_cluster (139)
Interaction (200)
Map_infoMapIIIPosition-2.04715Error0.00165
PositivePositive_cloneT10F2Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00033090
WBPaper00038491
WBPaper00049828
WBPaper00055090
Remarkdl1 : probably cytoplasmic
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene