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WormBase Tree Display for Gene: WBGene00001744

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Name Class

WBGene00001744SMapS_parentSequenceT10F2
IdentityVersion2
NameCGC_namegars-1Person_evidenceWBPerson36
WBPerson10953
Sequence_nameT10F2.1
Molecular_nameT10F2.1a
T10F2.1a.1
CE29472
T10F2.1b
CE32719
T10F2.1b.1
Other_namegrs-1
CELE_T10F2.1Accession_evidenceNDBBX284603
Public_namegars-1
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
229 Jan 2010 14:16:16WBPerson2970Name_changeCGC_namegars-1
Other_namegrs-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgars
Allele (35)
RNASeq_FPKM (74)
GO_annotation (29)
Contained_in_operonCEOP3260
Ortholog (47)
Structured_descriptionConcise_descriptiongrs-1 encodes a member of the glycyl-tRNA synthetase family that affects embryonic viability and spindle maintenance during anaphase.Paper_evidenceWBPaper00004403
WBPaper00004651
WBPaper00005654
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable glycine-tRNA ligase activity and protein dimerization activity. Predicted to be involved in diadenosine tetraphosphate biosynthetic process and mitochondrial glycyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Is an ortholog of human GARS1 (glycyl-tRNA synthetase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111204Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4162)
DOID:0110164Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4162)
Molecular_infoCorresponding_CDST10F2.1a
T10F2.1b
Corresponding_transcriptT10F2.1a.1
T10F2.1b.1
Other_sequence (114)
Associated_featureWBsf666457
WBsf666892
WBsf666893
WBsf666894
WBsf666895
WBsf981468
WBsf992318
WBsf226642
Experimental_infoRNAi_result (21)
Expr_patternExpr1013407
Expr1031037
Expr1156667
Expr2011947
Expr2030184
Drives_constructWBCnstr00037966
Construct_productWBCnstr00037966
Microarray_results (26)
Expression_clusterWBPaper00028451:Oogenic_protein
WBPaper00032528:L3_enriched
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00035073:mitochondria_protein
WBPaper00037047:aging_accelerated_insoluble_protein
WBPaper00037047:insoluble_protein
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038118:aak-2(gt33)_upregulated
WBPaper00038289:oocyte_protein
WBPaper00041072:UTX-1_interacting_protein
WBPaper00041097:pgl-1_downregulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046509:htz-1(ok3099)_upregulated
WBPaper00048910:mRNA-interacting_protein
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050599:nicotine(0.01mM)_upregulated
WBPaper00050698:DEP-1_interacting
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:germline_enriched
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053289:DREAM-target
WBPaper00053302:alovudine_24h_regulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053321:PGCs_enriched_NuGen
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053615:SMO-1_target
WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00055049:S.gordonii_upregulated
WBPaper00055354:Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Metformin_upregulated
WBPaper00055648:germline_expressed
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
WBPaper00057288:Cold_downregulated_protein
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_upregulated
WBPaper00058691:sin-3(tm1276)_upregulated
WBPaper00059174:MEG-3_interacting
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059605:MUT-16_interacting
WBPaper00060278:atp-2(RNAi)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061203:sin-3(tm1276)_downregulated
WBPaper00061341:28C_24h_downregulated
WBPaper00061527:abcf-1-C34B2.6_17049
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064163:ZNFX-1_interacting_embryo
WBPaper00064163:ZNFX-1_interacting_young-adult
WBPaper00064315:mes-3(bn199)_downregulated_EGCs
WBPaper00064315:mes-4(bn73)_downregulated_EGCs
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00064716:paraquat_upregulated
WBPaper00064789:Day12_vs_Day1_downregulated_neuron
WBPaper00064871:hypoxia_upregulated_F2
WBPaper00065158:AFD_depleted
WBPaper00065841:13_0
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4489_group_24
WBPaper00025032:cluster_27
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026952:class_A
WBPaper00030985:Serratia_marcesens_downregulated
WBPaper00032948:FedUp
WBPaper00035588:alg-1(-)_upregulated
WBPaper00036123:Cadmium_regulated
WBPaper00036123:Fluoranthene_regulated
WBPaper00037695:WC_5-day
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_regulated_old
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045263:isp-1(qm150)_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00048989:N2_allantoin_upregulated
WBPaper00048989:N2_rapamycin_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:cluster_1
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(53_min)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
Interaction (200)
Map_infoMapIIIPosition-2.04715Error0.00165
PositivePositive_cloneT10F2Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00033090
WBPaper00038491
WBPaper00049828
WBPaper00055090
Remarkdl1 : probably cytoplasmic
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene