WormBase Tree Display for Gene: WBGene00001744

WBGene00001744 SMap: S_parent: Sequence: T10F2
  Identity: Version: 2
    Name: CGC_name: gars-1 Person_evidence: WBPerson36
            WBPerson10953
      Sequence_name: T10F2.1
      Molecular_name: T10F2.1a
        T10F2.1a.1
        CE29472
        T10F2.1b
        CE32719
        T10F2.1b.1
      Other_name: grs-1
        CELE_T10F2.1 Accession_evidence: NDB BX284603
      Public_name: gars-1
    DB_info: Database (14)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 29 Jan 2010 14:16:16 WBPerson2970 Name_change: CGC_name: gars-1
                Other_name: grs-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gars
    Allele (35)
    RNASeq_FPKM (74)
    GO_annotation (29)
    Contained_in_operon: CEOP3260
    Ortholog: WBGene00068834 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00040130 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            WormBase-Compara
      WBGene00163469 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00104913 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00125595 Caenorhabditis japonica From_analysis: TreeFam
            WormBase-Compara
      WBGene00070632 Caenorhabditis remanei From_analysis: TreeFam
            WormBase-Compara
      WBGene00225974 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g4047 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g1229 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g111 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP26.g3769 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g19776 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g3720 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g10516 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP31.g17032 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g5101 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g8191 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g8195 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g13899 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g3219 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g16872 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00148.g5619 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_02424.g17174 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_10482.g22676 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-gars-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g12525 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_05260.g34678 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_06212 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_11032 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_008423 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_008425 Caenorhabditis remanei From_analysis: WormBase-Compara
      GCK72_008520 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g08170 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g1409 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g17302 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30025800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g7651 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00245771 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00262642 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00292623 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000000325 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      SGD:S000006285 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0027088 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-9174 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:4162 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2449057 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1307856 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: grs-1 encodes a member of the glycyl-tRNA synthetase family that affects embryonic viability and spindle maintenance during anaphase. Paper_evidence: WBPaper00004403
            WBPaper00004651
            WBPaper00005654
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable glycine-tRNA ligase activity and protein dimerization activity. Predicted to be involved in diadenosine tetraphosphate biosynthetic process and mitochondrial glycyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Is an ortholog of human GARS1 (glycyl-tRNA synthetase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111204 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4162)
      DOID:0110164 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4162)
  Molecular_info: Corresponding_CDS: T10F2.1a
      T10F2.1b
    Corresponding_transcript: T10F2.1a.1
      T10F2.1b.1
    Other_sequence (114)
    Associated_feature: WBsf666457
      WBsf666892
      WBsf666893
      WBsf666894
      WBsf666895
      WBsf981468
      WBsf992318
      WBsf226642
  Experimental_info: RNAi_result (21)
    Expr_pattern: Expr1013407
      Expr1031037
      Expr1156667
      Expr2011947
      Expr2030184
    Drives_construct: WBCnstr00037966
    Construct_product: WBCnstr00037966
    Microarray_results (26)
    Expression_cluster (139)
    Interaction (200)
  Map_info: Map: III Position: -2.04715 Error: 0.00165
    Positive: Positive_clone: T10F2 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00033090
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
  Remark: dl1 : probably cytoplasmic
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene